I have been on Humira for 5 months and even still, the day after I do my shot I am exhausted beyond belief. I do mine in the evening because I also do the Benadryl along with mine. I have spoken to my GI about
it and he said that as long as its not a constant exhaustion its ok, just have to deal I guess. =/
When I was on the Remicade I had the same effect, the doctor said that it was just my body recieving the medication and working harder than normal when I got it.