From Remi to Humira back to Remi question

I've done remi twice. The big concern is risk of antibodies having built up in your system from your first session. When I started the second time on Remi, I had my first infusion with no problem. But - with my second I had the big reaction - shortness of breath, heart palpitations, nausea. Now, it's not a given it will happen by any means - but it was in my case, so doc took me off. Good luck to you - I hope it does the trick.

I stopped Remicade due to allergic reactions and lose of response and now that I have exhausted all of my other options to treat both the Crohn's and arthritis, my GI has suggested going back on Remicade.  I voiced my concern and he said some people are able to do it successfully.  I asked my rheumy about it and she acted like it was not a good idea and too much of a risk, since I'd had allergic reactions to it.  Everything I find online about it says you are more likely to react to it the second time around, but I think there has been some people who handle it just fine.  I'm not willing to take the risk, since I already had reactions, but I would be willing to try it if I hadn't had the reactions. 

I was on Remicade for two years. I never had a complete response - had to get infusions every 6 weeks. At the end, 6 weeks still wasn't enough so we tried Humira for about 4-5 months. When it didn't work, I went back to Remicade. The first infusion went fine. The second infusion I got hives in my mouth and it didn't work at all -- could well have been a saline drip. But, as others have said, some people can go back to it! So, just talk to your doctor about doing pre-medication (Benadryl or steroids for a few days) to help prevent a reaction.