Still have my appendix and have had CD for 40-plus years. I think that each time one of these theories pops up that point to a possible cause or trigger for CD we ought to remember that the overwhelming preponderance of the research shows clearly that there is a cascade of genetic factors that need to be in place to predispose us in the first place . . . and that bacterial/immune reactions are likely one likely trigger ONLY if those predispositions are present. I suspect there are many possible triggers, and suggesting that "appendix out equals CD" is too simple.