Hi,
I have acid reflux and I started on Zantac, then Losec and am now on Nexium. These medications span approx 15 years. I have had crohns for 32 years. My GI has scoped me from the mouth down, or I will have an upper GI small bowel follow thru. I found that the Zantac worked great for about 3 or 4 years, then I needed the next in line Losec and finally Nexium. You need to take the med everyday, but you will want to when you are finally relieved of the painful burning feeling.
Julia