Hi! Sorry to hear you are so miserable. I know exactly how you feel. I had a fistulotomy a couple years ago and was miserable for months untill I took the Remicade! I was better like the next day! Seriously you need to take it to heal it up. Mine pretty much healed and the seton eventually fell out. I still have the "hole" where it was placed and I do have some drainage depending on how much I go to the bathroom but It is sooooo much better! Just take a few rounds of it and then stop if you dont want to stay on. the only things I take now are Apriso and maybe starting 6mp soon. Good luck, I feel for you guys!!!