Methotraxate Question - Worried

Hello Everyone,

I have been taking MTX now for 3 months, 10 mg/week with 1 mg folic acid, also take humira and entocort. When i started MTX, i had the usual side effects, nausea and just feeling tired, but the longer i took it, the less side effects i had and i though i was in the clear. This past week, i took my usual dose (granted 2 days late) and all hell has broken loose. I have this sick to my stomach feeling now for two days. All kinds of smells are causing me issues, although i have been eating and haven't thrown up.

Has this happened anyone or is something else going on with my tummy? Does my folic acid dosage need to be raised? I do take zofran for the nausea and it helps, but i'm worried that something else is causing the severe nausea this time.

I guess I should also add that my pooping has actually been really good last few days, while feeling the nausea, which is adding further to the mystery and my anxiety

Thanks!

Post Edited (Adam1980) : 6/20/2014 9:16:05 AM (GMT-6)

I have same issue. I hate side effects, and it doesn't seem to be helping crohns or RA

remember methotrexate is a old time chemo drug, although we take it in lower dosages. That said, it will or can cause alot of hat you are describing. the real question to answer is to determine if adding the methotrexate is helping improve symptoms or not. In my case, i slowly got sick on the drug, so slow that i just thought it was the crohn's. things like lost weight, nausea, not appetite and so forth. But we finally realized it was the metho. I had to stop work for 6 months to recover from all the side effects. to make matters worse, it did not put me in remission. bottom line, the GI and I did not check on improvements quick enough to decide if the drug as good for me. hope my experience helps you