Mast cells, DAO, and Histamines

Stumbled across something the other day that sent me on a research tangent. I am just wondering if anyone else has looked into the research or information on CD and the involvement of Mast cells, Histamines, and Diamine oxidase(DAO). And if anyone has tried DAO supplements, if they helped at all and what ones you tried? or a low histamine diet?

What I have found is a lot of research on the issue as far back as the 70's showing all kinds of stuff that pisses me off lol. Mainly that we have high histamine levels and low DAO levels(DAO destroys the histamines). unfortunately they use this information for the wrong purposes (in my mind).

I know I have a yeast intolerance and most of the yeast foods are on the high histamine foods list so there could be some interplay there (another round of chicken or the egg). A low histamine diet wouldn't be too difficult for me to accommodate, but I did order a DAO supplement today and am hoping that it will help.
Just curious if anyone has information I could use.

Thank you, it is worth a shot at least. I am not fond of the idea of where it comes from either but I am less fond of the idea of some of the other available options. Which one do you use? I ordered DAOsin from Swanson, there were a couple other options on Amazon.

I am gluten intolerant as well and keep that out of my diet as much as possible, it is the yeast issue I can never get completely away from bc it is naturally occurring. so I hope the DAO will help with that.(your red wine could have something to do with yeast as well?)

I have also found some information on foods that are supposed to contain or increase DAO. Green pea sprouts are supposed to contain it, that is a simple but detailed process that I am going to try as well. I also read that Mangosteen and butterbur supplements can increase DAO as well as chamomile, saffron, anise, fennel, caraway, licorice, cardamom and black seed. I have also ordered the mangosteen and black seed so hopefully the pig supplement will be temporary or only occasionally when I know I will be cheating.

Another study I stumbled on from June 2014 showed that chlorogenic acid decreases intestinal permeability, of course it was in rats. Hopefully their next step is humans. The only chlorogenic acid supplement I found was green coffee extract, the study stated that it is found in many fruits and plants but didn't state their source that I recall. DR Oz recommended green coffee a while back but I don't recall why, the manufacturers tout it as a weight loss supplement which is not what I need, but the reviews state that it is not a dramatic loss.

So it sounds like a lot of supplements, and nothing I found showed recommended amounts so I guess I will follow the manufacturers recommendations. but maybe if the chlorogenic acid helps with the permeability, and the DAOsin and pea sprouts can stop the histamine reaction that also damages the gut, while the mangosteen, and black seed help me to increase my own along with the diet changes I am hopeful to get myself a little closer to working order.

From what I read the peas should be sprouted in the dark to have more DAO, and used at the two leaf stage by placing them in a blender with water and making a smoothie with them. I have sprouted other seeds and legumes in mason jars on the kitchen counter with no problems. So I ordered some organic green peas for sprouting and will use the same method but in the cabinet and try not to forget about them.

With cheese I do not notice digestive issues but more mental/emotional ones. They make me extremely irritable, even angry like I could kill someone over the stupidest stuff. Walnuts too and I noticed they are on the high histamine list. Eggs are on the histamine releasing list, and in my mind histamine would be released only if you have a problem with it? but this is all new to me so I don't know.

For a laugh I just read that human placenta and seminal fluid are also high in DAO:-D

Happy to share, hopefully it will work out well for the both of you, all in the name of health and science of course;-)