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Azatheoprine is it not working ?

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Crohn's Disease
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Posted 8/13/2017 10:33 PM (GMT 0)
Hey guys Raffi again,

I was diagnosed 5 month ago with crohn's never got diharrea however I was put on prednisone for 3 month then on Aza, in the last two days I'm having lots of gas and the first day I got diharrea once and today twice does it mean that aza is not working and my disease is progressing or what any info would be appreciated.
Posted 8/13/2017 10:49 PM (GMT 0)
It takes aza 6 months to work. How much are you taking? You should be getting a blood test to see if it's at a therapeutic dose. Is it being combined with another medication like a biologic?
Posted 8/13/2017 10:55 PM (GMT 0)
I am taking 50mg twice a day I am about 60kg yea too skinny guy rolleyes
Yesterday I did blood test (CBC, ALT, AST) they were normal as the doctor said.
No I only take aza.
Posted 8/14/2017 12:58 AM (GMT 0)
It takes aza from 4 -6 months to start working. Did the blood test show that the WBCs got lowered? Are you on a brand aza or the generic one? When I took the generic aza, for 8 months my WBCs got elevated and only after switching to Imuran, they were down to the normal range which means inflammation was reduced.
Posted 8/14/2017 5:32 AM (GMT 0)
I'm on a brand called Azaram, and my WBC reduced from 9400 to 6400
Posted 8/14/2017 6:44 AM (GMT 0)
As others pointed out, it can take several months for azathioprine to work.

Additionally, your dose is a little low - it's typically 2.5mg/kg of body weight. That puts your dose at 150mg, not 100mg.

How long have you been taking it? Did you start at 50mg/day or 100mg/day? In any case, try going up to 150mg and see if you tolerate that dose ok. Continue to get regular blood tests.
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