Mine have gone up and down the last few years, even before I started Remicade and 6mp, so the doctor's haven't figured out what is causing it. I had an ERCP, MCRP and liver biopsy back in the fall and the only thing that showed up was slight dilation of the bile ducts. Dr. isn't concerned about
it and still has me on the 6mp (even though when I got a copy of my chart, he mentioned in my records about
5 times that I may have to come off of the 6mp, since that can increase your enzymes). Since mine have now come back down, they just want to keep an eye on them and maybe repeat tests down the road, if they come up again.