New to the site!...

 

 Hello Everyone :)

Im a little apprehensive to initiate this topic, Im a student studying dental.... I am doing a Project on Crohn's Disease, and was wondering if anyone feels comfortable enough to share some information. I figured here would be the best source... and would really appreciate any sort of help :)... i only have a couple questions that google isn't really helpful on :) , i understand this is a forum for those with the disease to communicate with others in the same situation...aware of this i hope not to offend anyone.

Hope to hear from someone soon :)

 

What would you like to know? lol gail

I don't think so... I think it's just the nature of the disease.

Thanks so much...

so its just a symptom that comes along with the disease?

researching the disease has me feel for all those suffering, and i hope that everyday everyone finds something to make this struggle easier...

The problem is due to the common mucous membrane immune system. The elevated TNF and IgE levels cause hypersensitivity to a wide array of irritants including common bacteria and allergens. I imagine that nutrient deficiencies resulting from malabsorption also contribute. Oxidative stress is poorly controlled because vitamins E, A and C are commonly deficient as are zinc and iron. Malabsorption also results in calcium deficit and taking calcium carbonate has the effect of reducing stomach acids thus diminishing the ability to absorb other deficient minerals (and carbonate is the least absorbable form of calcium, if also the cheapest). Of course, the teeth reflect the state of the calcium supply in the body, so they suffer as well. Malabsorption is a consequence of inflammation of the ileum and excess mucous secretion and commonly causes B12 and folate deficiency as well.

There are a number of syndromes relating to immune reaction to gut bacteria (the currently accepted view of the process of Crohn's) resulting from the immune cascade (TNF and IgE and a host of immune molecules) and the bacterial response (gut infection, release of endotoxins, diarrhea, fistulas and fissures, increased gut permeability, translocation of gut bacteria to the blood, liver, gallbladder, pancreas and others) and mimicking of body tissues by gut bacteria or their by-products resulting in auto-immunity toward a wide range of body tissues (mostly mucous membranes like the synovia).

To answer your question, throat, mouth and sinus lesions result from chronic inflammation of the gut. Even in well-controlled Crohn's, there is commonly irritation in the throat and sinuses.

My teeth have become sensitive at times. Some days are good and some not. Another thing that seems to effect alot of us are cryptic tonsils that dentist should be helping there patients with like how to cleanse those nasty things out properly. That would be a huge help .lol gail

i have never really had ne problems with ulcers in my mouth,most of my life my teeth have been fine,only 2 fillings due to hypo plastic teeth,then recently i needed to have one of my teeth pulled due to the fact it was completly rotten on the inside,no signs of decay on the outside of the tooth,didnt hurt to push on only thing was hurting was the jaw bone.I'm unsure why this happened and the dentist was baffled by it lol.