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Blood Test for Crohns and Colitis

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Crohn's Disease
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Posted 2/18/2009 4:50 AM (GMT 0)
Anyone ever have IBD serology 7 done. Is this accurate ? It can distinguish between crohns and colitis. What about CBC and ESR will this always show high if you have crohn ?

I tested positive for ASCA and Anti-ompC are high but CBC and ESR are normal.
Posted 2/18/2009 5:47 AM (GMT 0)
i had a test done by promethius labs...came back as UC not Crohn's after 20 years...i'm not buying it 100% though!
Posted 2/18/2009 7:27 AM (GMT 0)
It is my understanding (per my GI) that the IBD Serology 7 is quite accurate.  This newer test is supposed to be even more accurate than another test that Prometheus had several years ago.

No blood test is 100% accurate, though, and results should be confirmed through other testing (colonoscopies etc.).

The IBD Serology 7 was accurate for me.  My CBC is usually normal (except for occasional anemia), and my ESR is normal.

Hope this helps!

Posted 2/18/2009 4:52 PM (GMT 0)
My daughter had IBD Serology done, and the test proved to be very accurate. 
Posted 2/19/2009 1:52 AM (GMT 0)
Blossum

Did you have EGD or colonscopy biopsies to confirm the diagnose?
Posted 2/19/2009 1:55 AM (GMT 0)
Does anyone know if the symptom and diet for crohns and colitis are the same?
Posted 2/19/2009 7:01 PM (GMT 0)
My Serology test said UC with 95% accuracy, I think, but I ended up being diagnosed with Crohn's.  At the time of my test, they were calling it Indeterminable Colitis, but ended up going with Crohn's.

Posted 2/20/2009 1:58 AM (GMT 0)

My serology 7 test came back as negative.  My GI explained that fistulizing Crohn's tends to show up more on this blood test as opposed to non fistulizing Crohn's.  Interesting as well, my blood work ALWAYS came back as normal, even when they checked for inflammation levels.  Luckily, I was able to get my official diagnosis of Crohn's from the pill cam.

Posted 2/20/2009 1:05 PM (GMT 0)
The IBD serology 7 was what confirmed my suspected crohn's. I tested positive for omp-c. My cbc was only slightly above normal, so my GI said he won't rely on cbc as an indicator for me.
Posted 2/20/2009 6:10 PM (GMT 0)
Wow. I was diagnose with IBS constipation all this year. I glad that this new test is specific and 90% accurate
Posted 2/27/2009 6:40 PM (GMT 0)
INDIGOSUNRISE: you said that you were able to be officially diagnosed with Crohn's from the pill cam--what is that? I have recently been tentatively diagnosed with CD. I had the IBD serology test and it came back negative for both. However, both GI doctors I have seen believe that I have CD. I would like a way to obtain a definite diagnosis so I can accept it and move on. Thank you for your help!
Posted 3/2/2009 12:46 AM (GMT 0)
A pill cam is just what it says, breegs; a pill that you swallow (pretty big) that has a tiny minature camera in it. It takes photos at intervals, is..."recovered"....and the photos give literal snapshots of how things are at various points in the gut. It has the advantage that it can survey the whole gut, unlike all the different scopes.
Posted 3/2/2009 4:51 AM (GMT 0)
Kungalo,

Yes the symptoms can be identical, and diet wise they are very much the same, but differ from person to person.
Posted 3/9/2009 2:52 AM (GMT 0)

Sorry breegs! I haven't checked on this post for awhile.

I am so glad Snohare came along and answered that for you!

If you do have the pill cam, it is pretty cool!  To be honest, I was both sad and relieved when I got diagnosed.  I had had some pretty miserable symptoms with the Crohn's and not having a definitive answer for them was frustrating.  Plus, getting that diagnosis "opened the door" for me to get on Remicade, which has greatly improved my life. 

Best of luck to you and keep us posted!

Posted 3/10/2009 9:47 PM (GMT 0)

I'm very new here...still in the process of getting diagnosed, but my experience is that the blood test isn't that accurate. After my colonoscopy, upper endoscopy and biopsies indicated Crohn's, a lot of my symptoms subsided for a while, so the doc said we should confirm with the blood work. The blood work came back negative, and he told me that meant I didn't have Crohn's. OF course, I got super excited and relieved! But, going back for follow up tests showed that it probably was. When I asked the doc about the negative blood, he said the test is supposed to be 90% accurate, but in his experience more like 50-60%. Not good enough to tell someone they DON'T have it, in my opinion! I just did the pill camera last week as a final confirmation, so should get those results back then...

Anyway, I'm skeptical of the blood test...

Posted 3/10/2009 9:48 PM (GMT 0)
50% isn't much of a test, you might as well flip a coin...
Posted 3/10/2009 10:29 PM (GMT 0)
yeah Yes, please tell the medical profession. eyes Their grasp of statistics tends to be dire. (Same as the rest of us to be fair, just their incompetence has medico-legal consequences).
Posted 3/12/2009 2:23 AM (GMT 0)
My GI said my bloodmarkers were more indicative of Crohn's rather than Colitis, but this wasn't 100%. My physical symptoms and colonoscopy results could have gone either way....I'm still not totally convinced about what is wrong with me. I'm wondering what the likelihood of getting false positives with these tests are, does anyone know??
Posted 3/12/2009 3:41 AM (GMT 0)
just saw a new GI today due to ins change...he's keeping my dx as crohn's for the time being even though the promethius test said UC...he said all other indications are crohn's so he's more comfortable with that dx (for the time being...)
Posted 3/12/2009 6:56 AM (GMT 0)
i'm with u on the wondering about false positive business! i'm not convinced i have crohn's i believe it to be IBS but my doctors are 99.9% convinced otherwise!
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