Remicade Pretreatment with oral prednisone

I have. I also had an infusion where days after I had terrible joint pain, I couldn't even wash my hair or put on my bra it hurt so bad. After that the Dr had me take a high dose of prednisone the day before and day of. I never had the joint pain again. Not too soon after that I moved and had to find a new Dr, he said I should only be taking IV Bendadryl before that the prednisone didn't do anything.

Not sure which Dr was right, but never had the joint pain again and had a few more infusions taking Prednisone and oral Benadryl before and then several with IV Benadryl before.

They did not reduce my Remicade dose, just kept pre-medicating me with the Prednisone and Benadryl. It is interesting because I had 2 bad infusions in a row, one before the joint one with an allergic reaction and couldn't breath, then the next one with the joint pain after. But once they started pre-medicating me I did fine on all my infusions after that and I did them for about 5 more years.

I hope it works out for him, I was pretty nervous for the next few infusions after all that, but Remicade helped so much it was worth trying. I had about 5 -6 years with no sympoms and eating pretty normal.

Well after the 5 years my colon was doing pretty good so I was able to maintain remission for 2 years after that with just Sulfasalazine and probiotics. Then had a more severe flare and tried Humira last fall. I was hopeful because the Remicade worked so well but I did not do well with the Humira at all. I was on steroids almost the whole time because my doctor wanted to keep giving it more time to kick in and every time I dropped the steroids while on the Humira I flared.

Actually I think I am doing better now with the Humira out of my system. I am doing just Sulfasalazine, prednisone and vitamins and stronger probiotics. I finally got my prednisone down to 10 mg so I am starting Low dose Naltrexone as an alternative therapy.

I hope all goes well on Wednesday! All in all, the Remicade gave me the best quality of life for around 7 - 8 years and really even with these last flares I have never been as sick as I was the years before Remicade (knock on wood!)

I had been on Remicade for years and it's been working very well. but I had been off Remicade for 4 month, than go back to it. the Remicade did not seem to have the effect it use to. this is my 3rd infusion and it only lasted for 2 weeks. than the next 4 weeks, I am under extreme pain. I had to get some Tylenol just to get me going. I mention it to my doctor. He also gave me some Prednisone. 10mg per day. this is the 3rd day I'm on it. it didn't seem to help at all. I still have to take some Tylenol just to come my pain down. I will be give my doctor a call next week and see if I can increase the prednisone or not. not sure what else to go by with so much pain.

My husband also suffers from flu like symptoms including severe joint and muscle pain after a remicade infusion. This usually lasts around 2 days after infusion, and then he's back to normal. So, the doc put him on IV benedryl and 40 mgs of solumedrol, and now after the infusion, he runs a fever which is controlled with tylenol and his joint and muscle pain is mild and manageable.

PV

When I get my infusion I also have 40mg of prednisone added to the IV Bag as well as Benedryl (due to reaction, burning, numbness) and that has worked for me.

Hope that helps somewhat.

 

200 ml of hidrocorticoids (IV) + antihistamin (oral) and no problems at all.

75 mg of imuran helps in the effect and in delaying tha antibody production.

Hope it lasts.