(No Subject)

Hello,
My daughter has been diagnosed with Crohn’s recently. She is receiving a Remicade infusion,
When she got her induction doses, the doctor checked the level of medication on her system, it showed 4,5 which was low, but her symptoms were getting better, CRP, ESR… all the markers where ok.
We did 5ml every 8 weeks. After the levels of Remicade went down, 1.2 , The doctor increased the dose 10ml still kept every 8weeks.
Feb 9 before getting the infusion the from a blood , her CRP was elevated 10.2 , also we found out the level of Remicade is <1,5 which means there is no medication on her body
The good thing she don’t have antibodies.
I am very confused and worried need someone’s help… what is the right thing to do in this case?
The doctor said we can try to do 3 induction doses again, and after repeat every 4 weeks with a dose of 10ml to see if we can see any improvement with bringing back the medication otherwise we have to change the medication to Stelara, since the Humera is from the same family as Remicade .
Please if any doctors can advise
She just turned 11 so worried

Thank you for your support, yes, she was getting 5mg per kg, now we increased the does 10mg per kg every 8 weeks.
Overall she feels good, compared to before getting the Remicade , it was a magic for her .
The problem is, the Remicade level was to law inside her body, was 4.5 then 1.2 and now there is nothing it’s not staying inside her body for 8 weeks….
So the doctor recommended instead of 8 weeks give every 4 weeks to see if we can bring back the Remicade number inside her body. I am worried a lot …. What is a right think to do?

I would agree with @beave, your GI seems to be working hard for you. If she stays with Remicade, you might want further scopes done to get a look to see if things are really impoved.

Welcome to the forum. I do urge you to edit your post & make a title.

We have a few rules here at Healing Well & one of those rules are if a dr joins they are not allowed to give medical advice.

You are receiving information from members that has crohns disease or they have a family member with crohns.

When I was on Remicade I started at 5kg every 8 weeks after the loading doses. Over time this did not get me in remission. I ended up being bumped to 10kg every 4 weeks & did great with remission.

We all understand your concerns as it can be frightening especially when it comes to our young kids. Remicade seems to be working thank goodness.

Keep in mind, regardless of which medication used it's quite common having to adjust & tweak the dosage for the medication to be effective.

Keep us posted.