prednisone resistance, and emotional side effects of prednsione

i cannot seem to overcome the depression and anxiety that the prednisone is causing. in addition, the prednisone doesn't seem to be working- i have been one giant flare for months. i am seeing a counselor and am on an antidepressant, but feel scared and hopeless a lot of the time. i have had 3 remicade infusions, and at first it seemed to be working, but i got c diff and had to go back up to 30 mg pred a day. i really never seem to have a respite from pain, low grade fever and arthritis, even on the prednisone, and it is wrecking my emotional health. i am thinking that i may wean off of it- it is better to be in pain and stable than in pain and unstable.

if anyone has word of advice, please help.

Are you on 30 mg per day?  Are you taking 15 in the morning and 15 at night?  If you help to space them out at even intervals to keep the medicine more constant in your system that may help, prednisone is just terrible with the emotional side effects. :(  Good luck!

Hi I take my pred. in the am with breakfast the drugist told me to get it out of the way I think I slept better because I took it early . The only other thing I can think of is low roughage diet .I think you should stay on the pred. till you have something else from your Dr. to help you or at least talk to him about it .I know that the pred does seem to cause some problems with thinking it is common but I find this site really helps encourage and motivate me. Are you still on the Remicade? I had to go off it and now just 20 mg of pred. I feel I have put too much weight on but getting by for now . Hope the councelling is doing some good for you. Hang in there better days ahead .lol gail

thanks, marci. it helps