genetic testing

Alexandria2015

New Member

Joined : Jun 2015

Posts : 3

Posted 6/30/2015 1:38 PM (GMT 0)

does anyone know what the chances of 1 parent being a carrier of the CF gene and the other parent being negative and whether they will and what the percent number to pass on the children?

Gemsi

Veteran Member

Joined : Feb 2007

Posts : 1050

Posted 6/30/2015 10:47 PM (GMT 0)

There is a 1 in 25 chance of someone being a carrier of the CF gene. (uk statistics).

If you look at the full CF gene being part of a puzzle, there are 2 pieces to the puzzle. 1 piece is from each parent.

A carrier of CF has a healthy gene from one parent and a faulty gene from the second parent. A person with CF has a faulty gene from each parent.

IF one parent is a carrier and the other parent is not, then their child won't have CF, but there is a 50-50 chance their child could be a carrier.

IF both parents are carriers, then there is a 1 in 4 chance their child could have CF.

Hope this helps, tried to break it down as much as I can.

Gemsi

Veteran Member

Joined : Feb 2007

Posts : 1050

Posted 6/30/2015 10:49 PM (GMT 0)

Here is a diagram to make it easier to understand :)
VIEW IMAGE

Wiley Coyote

Regular Member

Joined : Jan 2015

Posts : 37

Posted 7/13/2015 12:22 AM (GMT 0)

Unless of course, one parents caries an untested for or unidentified CF gene, and then the child could have CF if the other is a carrier. And there is also such a thing as CF -like syndrome where someone only has one identified gene, and so supposedly is a carrier, but has all the issues of CF.

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