I've been on Cymbalta (with wonderful results) for almost a year. Makes me hyper (bouncing knee syndrome
). Take it in AM after breakfast. If I happen to forget and take it after 12 -- forget it, up all night!Also, depends on how much caffeine I have in my system too. So...say I take my Cymbalta around 10am & have 1 cuppa jo then, and another cup or 2 mid-afternoon...hyper city, can't sleep or else restless sleep, wild dreams and wake up really unrested. Agreed, work with your Doc and I hope that Cymbalta works for you as good as it has for me. And, also, it took the Cymbalta over 6 weeks to kick in for me, fwiw.