Hello,
If Protonix is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Protonix with Ampicillin, Iron, Nizoral or Coumadin. Reference: PDR Pocket Guide, 7th Edition
I do not have any other info re this med and not knowing what other meds you are on I would refer you to your physician as Darren has already wisely suggested.
Take care.