Hi Lugie, I've heard of some cases in which it's happened but it's not common. In those cases, the people were very overweight, rather sedentary and ate too many carbohydrates that overloaded their systems. In those cases, they lost weight and changed their eating and life styles. I don't advise anyone to stop their meds without approval of their doctors. As always, our glucose monitors keep us on track so we should always know what our readings are.