Hi,
I am on 94 units of lantus per day, I use the pen needle injector. When I first started I tried injections in my legs and found them to burn and be much more painfull. I now always give them in my stomach tword the sides. Because the pen only goes to 80 units I have to inject twice a night. I put 47 units in the left side then 47 in the right and this is mostly painless now. I never noticed a change in BS regardless of the location though.