We haven't experienced any of the side effects. It may just depend on the person's chemistry, and the mixing of the meds.
We have finally gotten to the point that we can wait an hour before eating, aftering taking it. The only 'side effect' I have noticed, is if I eat something sweet after taking it, I get very nauseated. The solution to that was.....quit eating sweets for at least 2-3 hours later. The nausea didn't last long, and I learned that lesson in a hurry.
I just wish I had the determination my husband has. But, I fudge, and sometimes, literally! hahahaah