Everyone's experience seems to be different regarding biopsies. Some breeze right through them, while others (like myself) find it really rough. Some docs do give something to calm you prior to the biopsy. Mine didn't. I got a horrible backache, and since they didn't have Darvocet in the short-stay OR, and only morphine, I held out as long as I could...but finally had to ask for a shot. You stay in the hospital, lying on your right side on a rolled up towel (for pressure to prevent internal bleeding) for a number of hours and then are discharged. I was able to go to work the next day, but was somewhat tender for a couple of days. They advise against heavy lifting (anything over 10 lbs.) for several days to a week--again to prevent internal bleeding.
Connie