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Pegasys, Sovaldi and Ribavirin TX?
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Hepatitis
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ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 7/23/2014 8:47 PM (GMT 0)
First, let me say how glad I am to have found so much helpful information here.
60 years old, Geno 1a, no biopsy, so little to go on there...have probably had this lurking within for 40 years, probably harking back to the naive, foolish days of a briefly mis-spent youth, but I'm not 100% sure...just found out early this year though routine bloodwork. Have been seeing elevated liver enzymes for about
5 years but they just tested for Hep C this year.
Going to start tx next week: Pegasys, Sovaldi and Ribavirin, so I've been reading all the threads I could find that pertain to this specific path so I can try to prepare. Must say I'm nervous about
it when I read about
some of the side effects. Hoping to at least keep working most days. (I work a 4 days week, so will do the injection on the night of my last work day each week, so I've got 3 days each week to rest up or whatever before starting all over again)
If anyone has any tips, advice or encouragement on going forth with this, I would really appreciate it!
Again, I am grateful for everyone who has taken the time to share their stories and experiences in this forum...It's nice to be able to relate, commiserate and listen & learn.
**David**
Veteran Member
Joined : Nov 2009
Posts : 3708
Posted 7/23/2014 9:24 PM (GMT 0)
I've done the pegasys (interferon) and ribavirin twice. It worked both times. The first time, a cerebral hemorrhage derailed it. The second time was a year after my transplant and I've been undetectable for nearly 3 years now.
Instead of injecting after work, do it the morning of your last day of work. I would do my shot on Friday morning and the effects didn't start until that evening. Saturday, I would be sick, flu like symptoms, fever, achy, etc.. Sunday I'd feel a little better and Monday I'd work a half day in the afternoon.
As far as injection sites, I would switch from left leg to right leg to left stomach, to right stomach. That way each spot had an injection once a month. Another thing is to pinch the skin between your fingers and inject there. It doesn't hurt much, but that makes it hurt even less.
Drink lots of water every day. Three quarts at the least.
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 7/23/2014 10:49 PM (GMT 0)
Thank you for that idea...how many hours did it typically take to react? (I work 10 hours and have a half hr drive home...so want to have time to get there before hitting the unknown ..or vice versa).
After you finished with treatment, how long did it take to feel sort of good again?
I've been working on increasing my water consumption every day. Can green tea or chamomile tea be included with that? And I've pretty much stopped taking most of my supplements for now, other than a multivitamin w omega 3. Wondering about
B 12....
I appreciate you taking the time to reply to my post with this info.
**David**
Veteran Member
Joined : Nov 2009
Posts : 3708
Posted 7/24/2014 12:31 AM (GMT 0)
The pegasys took about
10-12 hours to hit me. It would take an hour or two for the full effects. It didn't prevent me from driving or cooking dinner, but I tried no to have to do anything while feeling crappy. Just like the flu, I wasn't crippled though I didn't want to have to do things. Also felt feverish, then alternating with feeling chilled.
I finished treatment in late 2010.
The pegasys effects last a while, maybe 4 months, tapered off quickly at first. Remember, I did it for 15 months. In your situation, you're doing it for a lot less time. Your side effects ought to be gone in a short time. Besides, curing Hep C is a lifesaver. I had it for 40 years, then my liver went downhill in a very short time. There's no way to know when the virus will raise its ugly head.
themiz
Veteran Member
Joined : Feb 2013
Posts : 1891
Posted 7/24/2014 2:20 AM (GMT 0)
Hi ZenCat,
First let me welcome you...and so glad you found us!
My husband treated twice, 24 weeks each time. He took the interferon Friday, after work the first treatment. More difficult as the months ran on. The 2nd time he did not work, was having too many issues with cirrhosis. He was much more ill the 2nd time than the 1st time. So worth it to get rid of Hep C. Big Hugs
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 7/24/2014 2:44 AM (GMT 0)
Thank you , miz.
After encountering some pretty grim tales, it is inspiring and reassuring to know there are those of you, like David. out there who were still able to try and maintain some semblance of normalcy throughout treatments, in spite of the physical challenges. That is going to be my inspiration. (that and hope)
I know I'm fortunate to only have to get through 12 weeks. Should be able to go with the flow for 12 weeks.
Felt pretty run down, achy and tired for the last few years anyway, so in the whole scheme of things......yeah...And the light at the end of the tunnel will be "undetectable"
Thanks for listening and thanks for sharing. It helps.
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 9/6/2014 12:33 AM (GMT 0)
Not sure if this is the right place for an update, but here it is, for what its worth...4 weeks into tx and Undetected, (down from vl 2,183,000). Blood counts are decent, ...sides haven't been too bad, but I for sure can tell there's stuff going on ...some days not as good as others, but overall, I cannot complain and I don't regret going ahead with this course of tx. Haven't missed any work and I feel pretty decent most of the time. Insomnia, itchy red eyes and tired sometimes...had a really sore tongue/mouth for about
a week, but Vit B-complex seemed to clear that up. Starting my 6th week , so about
halfway there. Best wishes to all.
And Beware the Jabberwock...
themiz
Veteran Member
Joined : Feb 2013
Posts : 1891
Posted 9/6/2014 1:12 AM (GMT 0)
Zen,
So glad to hear you are continuing work, as you hoped. Best, best news in going undetected! It is such a good feeling when you get that good news.
You are posting in the right place, and we can see your history on treatment this way. Insomnia and anxiety both seem to be a common complaint with the riba treatment. Some get Ambien or Xanax to ease the sides for a few weeks. Thanks for checking in to update us. We have seen many SVR results here. Can't wait for you to join the ranks. Big Hugs
ppm guy
Veteran Member
Joined : Apr 2010
Posts : 1261
Posted 9/7/2014 6:54 PM (GMT 0)
congrats on being undetectable!!!!
that should make the remaining 8 weeks, much easier.
best always
barry
MamaLama
Veteran Member
Joined : Oct 2010
Posts : 4907
Posted 9/7/2014 10:33 PM (GMT 0)
Zen...so glad to hear things are going so well. This is what our dragon slayers pray for. Only a few more weeks! Hugs,.Mama Lama
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 10/3/2014 9:13 PM (GMT 0)
Another check in....latest bloodwork looks good...platelets even went up, HCT is at 33.1, HGB at 11.3..overall, numbers look pretty decent.....
Not feeling too bad. Some days maybe a headache, but seems like sinus and allergies are intensified .....had to get some drops from eye dr. for dry eye...meds plus allergies giving me itchy dry eyes..
still have some sleep problems, but take a unisom every night....may not keep me asleep all night, but at least I can drift off and avoid the anxiety of laying there wishing I could just fall asleep....
Only 2 more Pegasys shots to go.....and the 3 weeks worth of Sovaldi and Riba and it's all done. I can't say I have had any regrets at this point about
going with this tx....the fear beforehand was worse than what I've experienced since starting....Can't say it was fun, either....you can tell there's stuff going on even when you just can't quite put your finger on it....but hopefully, whats going on is the virus going down and staying down for the count.....hope i've maintained the undetected from week 4.
I appreciate everyone who contributes to this forum...it really helps so many people to have this outlet to turn to. Wishing the best of health and happiness to all. Peace.
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 10/3/2014 9:13 PM (GMT 0)
Another check in....latest bloodwork looks good...platelets even went up, HCT is at 33.1, HGB at 11.3..overall, numbers look pretty decent.....
Not feeling too bad. Some days maybe a headache, but seems like sinus and allergies are intensified .....had to get some drops from eye dr. for dry eye...meds plus allergies giving me itchy dry eyes..
still have some sleep problems, but take a unisom every night....may not keep me asleep all night, but at least I can drift off and avoid the anxiety of laying there wishing I could just fall asleep....
Only 2 more Pegasys shots to go.....and the 3 weeks worth of Sovaldi and Riba and it's all done. I can't say I have had any regrets at this point about
going with this tx....the fear beforehand was worse than what I've experienced since starting....Can't say it was fun, either....you can tell there's stuff going on even when you just can't quite put your finger on it....but hopefully, whats going on is the virus going down and staying down for the count.....hope i've maintained the undetected from week 4.
I appreciate everyone who contributes to this forum...it really helps so many people to have this outlet to turn to. Wishing the best of health and happiness to all. Peace.
themiz
Veteran Member
Joined : Feb 2013
Posts : 1891
Posted 10/3/2014 9:45 PM (GMT 0)
Zen, You had the nasty interferon treatment. But your odds are very good with eradicating Hep C ! Almost there! I am glad you are almost done, and can get back to living life! Big Hugs
**David**
Veteran Member
Joined : Nov 2009
Posts : 3708
Posted 10/4/2014 4:04 AM (GMT 0)
Hi Zen,
The last couple of shots were the toughest. I never minded the shots until the end, when I wanted to be over with it, knowing that I'd been undetectable for so long. What I'm trying to say is...don't stop. I didn't and I've been undetectable for 3 years.
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 10/17/2014 2:10 AM (GMT 0)
Finished the last Peg pen tonight......6 more days of Riba and Sovaldi and the Finish line is in sight.
Will have viral load drawn next week.
Hope to feel a little more normal soon, but feel fortunate the so far, in that the sides (the ones I'm aware of, at least) have been pretty manageable. Really tired. My scalp has hurt for weeks...Eyes itchy and dry, have to use drops...Sleep at night is a series of 2 to 3 hour naps...Little aches here and there , but seems like I kind of had that going on anyway....a few headaches and some sinus pain...I have come close to some frustration moment meltdowns...but mainly I just try to stifle the moody crap until it passes....
Just wanted to share this final part my tx to date.
New drugs are arriving now, so good news for those who are waiting. Anybody who still is on this triple tx, tho'...I hope you are faring well on it. I know everyone is different, but I found it to be tolerable and the 12 weeks went by pretty well for the most part.
Thank you and best wishes to everyone out there.
ZenCat
New Member
Joined : Jul 2014
Posts : 16
Posted 10/23/2014 4:07 AM (GMT 0)
Finished my 12 weeks today...got the last pills down tonight. G'nite Sovaldi, good-bye, riba....
Now I wait. Getting a viral load now, eot, and again in 6 mos. Anxious to see what's next.
Wishing everyone the best.
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