Chronic Hepatits B and fatty liver

Hi,

I am 27 years old. I done blood test which told HbsAg postive. Doctor told that he will not start the treatment , but he will do monitoring for very 4 months. these are details of blood test.

ALT 76IU/ml

HbsAg - Reactive

HbsAb < 10.0

HbeAg - Non Reactive

HbeAb - Reactive

Ultra sound scan shows i am having fatty liver and also i have diabetes too. i am taking medication for diabetes Janumet 50/1000 daily once

he told that i am infected from last 10 years, is my condition serious. please advice.

Hi,

Thanks for reply.

2 weeks before only i came to know that i was having chronic infection.

My doctor told me , liver is working proeprly, so we will monitor for every 4 months, if the virus causing damage to liver, then he told he will start the treatment.

this is the details in blood report for liver fucntion

Total Protein - 74g/L

Albumin - 48g/L

Globulin - 26g/L

A/G Ratio - 1.8

Alakline phosphatase - 82U/L

Bilirubin(total) 10umol/L

GGT = 37U/L

AST - 43U/L

ALT -72U/L

Alpha fetprotein - 3.4ng/mL


i am using medication for diabetes from last 2 weeks only. I changed my diet and lifestyle, eating more fruits and leafy vegetables, and whole grain breads. My blood sugar level in fasting come down to 6.2 from 8.4 before starting medication and doing regular excercises.

I have appointment again on September, he told he will done blood test again, based on that he will start treatment.

Thank you.

ppm guy said...
hello Dinesh and welcome,
your numbers suggest a chronic infection, with low risk of liver damage. you diabetes can complicate things.

did you have a biopsy and viral load done? a biopsy can stage your fatty liver, and the viral load will tell you if the infection is replicating.

frequent bloodwork of your liver function and lipid panel, will give you feedback on how well your doing.
if you are just being diagnosed for the 1st time, make sure your medical team walks you through necessary life style changes..

best of luck to you, and let me know how your getting along. we have a hep b clinical trial thread for a long time member. you will find it interesting. some of your issues are similar.

As ppm guy suggested, get a test on your viral load. This will give you an indication if your virus is replicating. What can occur in Chronic Hep B infections (such as mine) is that the virus can become "active" and quickly get a high number. For example, if you're viral load is a low number less than 1,000 in one test and then suddenly becomes in the hundreds of thousands in a test 2 weeks later, then it can be concluded it went active and you'll need to start treatment immediately. To be honest, they said this would be the best time for a treatment when a chronic infection is active. If you are at a low viral count and continue to be that way (even if your number goes from say 100 i/u to 200 i/u on the viral load count) then you won't need treatment and just monitoring.

Additionally, you won't need a liver biopsy just yet. There are other options that don't puncture you such as a Fibroscan. Consider this if you need it. To me, it sounds like your doctor is following protocol and treating it as a new non-chronic infection even though he knows it's chronic. Usually that protocol states that monitoring is required for 6 months after the first discovery to determine it's stage and consider it the chronic phase then after 6 months infection.

Your exercise and diet sound good, keep up with it (I wish I was doing the same but I'm getting back on track ). Also, don't let any of this get to your head and try not to think about it. Continue to live a normal life!

P.S.
I'm the member with the Clinical Trial thread mentioned in this reply

You are doing great!!!

Your A1C has really improved. I think your medication has made a big difference. And you're sticking to your diet and it shows.

Your ALT really dropped. Congratulations!!!

What can I do immediately to regain some muscles and weight before further prescription for long term treatment?