My little sister has had IBS-C most of her life and takes Zelnorm; she swears by it. I don't know if you have ever tried it but in Mexico it is OTC (unlike the US) and she only goes to one place she trusts (
here) because it's by Novartis who are the name-brand guys and not the generic guys. She's really picky.
By comparison, the cliché "difference of night and day" is what she claims it to be now as opposed to before she started taking it. I of course am not a doctor but from visual experience lived through my sister I can say that it seems like zelnorm could be a possibility for relief. We both wish you well...