Hi! I've been doing my MTX injections since last Nov. I had to be switched to injections due to malabsorbtion from the pancreatitis. I give mine in my thigh in the muscle it's not bad at all. My dose just got increased from 12.5 to 20mg last week. You definately absorb more of the MTX through injection as with usually any drug by mouth you are only getting about 50% of the amount due to digestion proccess etc.
Hugs!
Cathy