Just started on plaquenil could Dr be leaning towards lupus?

It has been a while since I have posted. I am currently seeing a neurologist for brain lesions, numbness patches on legs and hands and feet, burning and tingling on face, and brain fog issues.
I am also seeing a rheumatologist for positive ANA 160 homogeneous pattern, joint pain, swollen joints in hands and wrists, elevated CRP and sed rate and just overall not feeling well. All blood work with the above mentioned is normal.

I have been seeing these Drs. for a year now with no diagnosis. I was started on Cymbalta and Diclofenac. My Rhuemy thought it could be human parvo virus B 19 ( fifth's disease) since my CRP and sed rates were not coming down and remained high... at that time he put me on Rayos 5 mg. Next visit in July CRP went back to normal and sed rate dropped. Went back in Sept and CRP slightly high again and SED rate is highest it has ever been. I was started on Plaquenil 400 mg a day. My blood work will be retested in NOV.

Can brain lesions occur with lupus? Does this sound like lupus?

Plaquenil is used with several auto-immune diseases, so it really doesn't indicate that the Drs are thinking about Lupus.

You should ask your Drs what direction they are thinking - sometimes they don't want to say when they aren't ready to diagnose you yet, but you can ask and even press a little if you are really clear with them that you just want a general idea and are also interested in what, if anything, they have ruled out.

The kinds of tingling, etc that you are seeing a neurologist about can, in my experience, be caused by inflammation from an auto-immune disease like Lupus. Typically the inflammation markers in your bloodwork would be higher when you're experiencing these symptoms, but not always.

Generally they try prednisone (which I see Rayos is) in these situations... but 5 mg isn't very high. I'm unclear - was the Rayos only for a month or are you still on it?

Take care,