Posted 7/7/2014 11:01 AM (GMT 0)
Hello,
Please remember that there are 101 reasons why people with Lyme can be antibody negative. A good doctor will make a clinical diagnosis taking into account your history and symptoms, and not rely on antibody tests at all.
The 23 and 39 bands are extremely specific for Borrelia burgdorferi , and an IND is stronger evidence than a negative, so this is additional evidence your LLMD can take into account. Many mainstream doctors insist that IgM bands are worthless without a postive IgG, but this is because they are following CDC and IDSA flawed protocols, which are themselves worthless. Long ago it was found that in chronic Lyme a person may have IgM late in the disease without IgG.
As for 41, this band represents the flagellin protein. Flagellae are a "tail" in some bacteria; in Lyme it's internal, nt sticking out, and is more like the propelling mechanism on an outboard motor, helping it to corkscrew through tissue.
Band 41 is extremely common in Lyme, but not considered specific, as there are other bacteria which will cross-react with it. There is a band called "41 int" which has been used in Europe; this represents a part of the flagellin protein which IS specific to Borrelia - however, it's not widely in use.
If your LLMD has made a clinical diagnosis of Lyme, you can have confidence in that. However, if you want more assurance for yourself and can afford it, there is the Advanced Laboratory culture test. This is an excellent test which can actually grow the bacteria from your blood, and has detected it even i people who have had long-term antibiotic treatment.
Sadly CDC are currently engaged in an attack on it, hurling false accusations and attempting to shut it down, as it proves that everything they have said on Lyme is not true.
Elena