here is the site that I use to help interpret them:
www.reocities.com/HotSprings/Oasis/6455/western-blot.txtAn IgM result means that you have an active infection. It once was thought to mean an 'early' infection, but has since been revised. IgG means that the infection is at a later stage. The more +'s you have beside a number, the stronger the reaction.
IND means indeterminate - not negative, but not quite strong enough to be "fully positive". But it means that you reacted on those bands and should be considered, especially when they are Lyme specific bands.
A "Lyme specific band" means specific for Borrelia Burgdorferi, sensu stricto - Lyme disease in the strictest sense. There is only
one on the over 300 known strains of Lyme that is considered Bb, ss. Nothing else will turn a Lyme specific band positive other than Lyme disease.
Bands 18 & 41 (whether in IgM or IgG) are indicative of the tail of the bacteria, which can cross react with other Spirochetal bacteria such as Relapsing Fever, Pintas and Yaws, and Syphilis.
Okay, you tested positive or IND for these bands: 31, 41, 58, 34, 38.
Band 31 indicates OspA - Outer Surface Protein "A" - and is specific to Lyme.
Band 34 indicates OspB - Outer Surface Protein "B" - and is specific to Lyme.
Band 58 evidence of being in Poland from B. afzelii:
www.ncbi.nlm.nih.gov/pubmed/9972057www.ncbi.nlm.nih.gov/pubmed/18328630www.ncbi.nlm.nih.gov/pubmed/23540208With a very interesting conversation going on about
this here:
www.lymeneteurope.org/forum/viewtopic.php?f=5&t=3592&sid=4e5bf09031b0550b98e3e30c61a940ebAnd - for those of you that like this stuff - I learned something new!! Band 38 indicates flagellin B!! A flagellin is the "tail" of the bacteria and there are two parts - A (like an outer coating) & B (like a core of the tail). Band 41 indicates flagellin A, so band 38 is detecting the outer sheath of the tail of the Lyme bacteria:
www.ncbi.nlm.nih.gov/pubmed/9573194