So I was looking up something for a member, and came across something that I believe just might show that band 23 is Lyme specific!
All of my research had led me to believe that band 23 showed that although it was specific for OspC, it was not specific for the one strain of Lyme everyone tests for(even though there are over 100 strains that have been proven to cause human illness).
Until I came across these two studies:
www.ncbi.nlm.nih.gov/pubmed/?term=PMID%3A+8225587&p%24a=&p%24l=DefaultSite&p%24st=m"We have found that sera from patients with early stages of Lyme disease contain predominant immunoglobulin M reactivity to a major 23-kDa protein (p23) from Borrelia burgdorferi 2591 isolated in Connecticut. "
and :
www.ncbi.nlm.nih.gov/pubmed/10645981"The bands found to be most reliable for the identification of strain B. burgdorferi B31 by IgG WB were those representing the 93, 39, 34, and 23-kDa proteins."
Anyone else read the same things as I do????