Most everyone with a chronic infection like Lyme will test high for quinolinic acid. It is part of the inflammatory process that occurs over and over in chronic infection.
I've never had twitches or spams all over but decided to recently study it because so many people on this forum have problems with it. Here is what I found and what I would do if I had it as a problem.
When examining mycotoxins, or fungal metabolites that are toxic to humans, it has been shown in research that phenylalanine can block the effects of ochratoxin, one of the mycotoxins. Urinary phenyalanine excretion increases with fungal infections. So in essence, the body increases phenylalanine to protect itself from certain fungal toxins. There are urine tests that test for the mycotoxins, I would have one of those just to rule it out. I would also go on a PKU diet to see if that helped reduce phenylalanine levels. Here is some info on Adult PKU, which in a way is what I think some of us have due to our chronic infections and BH4 production problems. Disregard the supplement information. Maybe I would eat LNAA's as my only source of protein (tryptophan, tyrosine and the branched-chain amino acids.)
/www.meadjohnson.com/pediatrics/us-en/sites/hcp-usa/files/LF873REV-10-05_1.pdfOur levels of BH4 are constantly being threatened because of our chronic infection and there is an enzymatic link between elevated phenylalanine, decreased BH4, and neopterin. When you combine all of this with the symptoms of not enough BH4, you get twitches and spams as adverse reactions.
I am not diagnosing anyone, I'm just telling what I would try if I had this problem.