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Mepron vs Flagyl

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Posted 6/3/2016 3:28 AM (GMT 0)
Hi everyone,

I am into my third month of treatment, last month Mepron was addressed to my doxy regimen and all I felt was total fatigue, brain fog, and much more intense nausea. My Dr suggested this protocol isn't working (although I thought those could be signs of herxing???) since I haven't shown any improvements at all. He suggested a new abx and instead of Mepron to start flagyl. I really didn't mind the Mepron but seem to be finding mostly horror stories for the flagyl... Starting to wonder if I should ask him I try one more month with the Mepron before giving up on it.

Has any one else has a similar experience? Did you stick it out and find improvements? Are people finding one to be more successful/stronger than the other? Thank you for your time and replies!
Posted 6/3/2016 4:14 AM (GMT 0)
Micha - Mepron is for Babesia. Flagyl is usually added as a cyst buster for lyme.

I haven't heard of Flagyl being used for Babesia.

Do you think your Dr. has concluded you don't have Babesia since he suggested it wasn't working?

So, you were on Mepron for one month only? That isn't sufficient time to know.
And..fatigue, brain fog...even nausea could very well be a herx.

I think it's a good idea to ask to try it for another month before throwing in the towel.
Posted 6/3/2016 4:24 AM (GMT 0)
Thank you, Girlie.
You confirmed what I thought, although I was certainly confused because he basically said they were used the exact same... I don't want him to feel I'm challenging him either... I definitely have the symptoms for babesia and do not want to ignore treating it.
Posted 6/3/2016 5:21 AM (GMT 0)
Micha - maybe do a search on this forum - and see if Flagyl is prescribed for Babesia.

I Haven't heard of it...but I don't know for sure.
It's certainly not one of the commonly prescribed med.
Posted 6/3/2016 1:27 PM (GMT 0)
Both Flagyl and TindaMax do have anti-parasitic properties. So they may have some benefit treating Babs, but they are low on the list of proven remedies. I would stick with Mepron (w/ Zith) for a full 4 months if you can afford it. If I recall weeks 4 thru 9 on my first round on Mepron were pretty rough before seeing improvements.

Have you considered herbals like Cryptolepsis, Sida Acuta, and Houtunyea (sp?) in parallel with Rx?
Posted 6/3/2016 2:40 PM (GMT 0)
Micha, also make sure you're taking your Mepron with fatty foods.

The more fat you take with it, the more medication you'll absorb, and that stuff is too expensive to just pee out :)

Babesia is usually treated a minimum of 3-5 months, because that is the average life span of a red blood cell where the parasite likes to hang out.
Posted 6/3/2016 2:40 PM (GMT 0)
Tickbite666, I have started looking into herbs. I've just been concerned they may react with my abx. I've tried to bring this up with my LLMD but he declines any participation in alternative medicines... I acknowledge I'm missing out on some beneficial avenues which is why I've been trying to research that more. Thank you
Posted 6/3/2016 2:57 PM (GMT 0)
Flagyl is not curative when treating Babesia. It can help greatly as it can affect other parasites that often coincide with Babesia infections. The people who can't tolerate Flagyl most likely have additional parasites and the die off is too great for their system to handle. We just don't know what we have and have to guess at what we're treating. Positive tests are great, but there just aren't enough tests to show everything we've got.
Posted 6/3/2016 3:29 PM (GMT 0)
Herbs recommended by Buhner can all be taken with antibiotics.
Posted 9/15/2016 7:14 PM (GMT 0)
My doctor also put me on Doxy and Flagyl for Lyme & Babesia. He's a prominent ILADS guy. His first choice is Mepron because there isn't as much research on Flagyl, but he told me that he uses it all the time when when insurance doesn't cover Mepron.

@Micha085 how did you end up doing on this combo?
Posted 9/15/2016 8:09 PM (GMT 0)
There are some herbs that may not go with antibiotics.


Artemisinin is one.

Someone posted Cryptolepis.

ABX that they may not go with: Rifampin, biaxin

It has to do with the Cytochrome P450 enzymes.
Posted 9/15/2016 8:15 PM (GMT 0)
Welcome to our community, HudsonValleyMom!

We suggest all new members take a look through the thread at the top of the page titled: "New to Lyme?..Start here!" It's packed full of useful information.


I hope you find this to be a supportive, and knowledgeable community.
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