Vitamin B12 Supplements

I didn't do any research - I went the easy route - and use a brand by TJ's that you place under your tongue. I also take methyl - B12 for a particular gene mutation. Hope someone comes along who is better informed than me.

I take one from our grocery store...the brand is Trophic - but I think it's only sold in Canada.

My B12 levels were over the high end of range...so it's working.

I thought its easy to get this from food: 100 gr of cooked beef liver will get you 1386 %DV
Unless you are vegan

Thorne Research-B complex #12 (I've also tried their Basic B complex with good results). These are good mostly for people with methylation issues (mthfr gene problems) and have trouble getting rid of toxins because of it. You can get this on Amazon or iherb.com

I use Yarrow brand, sublingual methyl B-12. I did the cyano B-12 shots and had to literally take a 2 hour nap each day after I did the injections because it took so much energy for my body to convert it over to a usable form.

Stanislav said...
I thought its easy to get this from food: 100 gr of cooked beef liver will get you 1386 %DV
Unless you are vegan

Some people like myself are not able to utilize B12 or Vit D from food. I also cannot absorb either one from Sunshine, particularly in the latitude I am in.

julymorning said...

Stanislav said...
I thought its easy to get this from food: 100 gr of cooked beef liver will get you 1386 %DV
Unless you are vegan

Some people like myself are not able to utilize B12 or Vit D from food. I also cannot absorb either one from Sunshine, particularly in the latitude I am in.

The type of B-12 you need to take depends on your genetic makeup. For someone like yourself that has difficulty with the regular cyano or methyl forms of B-12, a combination of adenosyl and/or hydroxocobalamin would be advised. As your B-12 levels rise and methylation increases, problems may develop if your detox pathways are functioning well. Glutathione is a he11 of an antioxidant.

There's overmethylating and undermethylating. Your body can break down too much, too fast. Symptoms are similar to undermethylating.

It could be that your body is trying to push out the toxins too quickly, but also that your neurotransmitters are out of sync.

Georgia Hunter knows best, though. I am not that learned on the subject.

But, I think that's the intended point - overmethylation.

Antonio is correct. Methylation plays a big role in oxidative stress and nitric oxide formation. When we have so much oxidative stress that it causes us health problems, our body does whatever it can to reduce the damage that is occurring. It may have an epigenetic shift in genes to decrease methylation and oxidative stress or it may deplete a catalyst like Mg or Cu to reduce oxidative stress. This also slows methylation and reduces free radical formation. In essence, we can have two outcomes for the same pathway. We have our original methylation pathway that when functioning correctly, kills many pathogens but the oxidative stress it creates to kill the pathogens overcomes our ability to reduce it down to harmless by products and cellular damage occurs. That same pathway can be diminished through actions taken by our body so that the oxidative stress is reduced and less cellular damage occurs. The pathogens basically get a free ride (with limits of course.) Our body changes its ability to find and attack them.

Revving up a diminished methylation pathway kills more pathogens and many just can't handle it. That's often whey you hear the term to treat "low and slow."

Huddie said...
GH,

I always learn so much from you. You are impressively intelligent in your knowledge of our bio-chemistry/Lyme, and I'm sure much more!

I used to be intelligent before lyme, now I do my best. That said, can you explain this to a lay person? Are you advising yes on methyl supplements or no?

I do not have any data on whether my methyl pathways are impaired. I do take methyl folate and methyl B12.

Thanks.

Thanks for the compliments, hopefully I have helped someone. I used to be fairly smart before I really started aging. Now I'm just average but try really hard. I don't have a recommendation on supplementing B-12 because I don't know the specifics of your issues. A recommendation without the specifics is careless. Increasing methylation may be beneficial or may be harmful depending on your situation. I would think a dietary change would be more helpful than anything you can do and I say that without even knowing what you eat. You can eat better than everyone else but that still doesn't mean you can't improve your situation through dietary manipulation. Knowing what you ingest is the key and what makes you feel better or worse. Over time, you can figure out things you never would have known.

Huddie said...
GH,

Thank you. I eat very well. Organic, mostly plant based, a little lean organic chicken or turkey. No sugar, gluten, dairy, etc...

My real question is how do we know if we should or shouldn't be taking a methyl supplement? I seem ok but have no way of knowing. I guess I have to get tested for that pathway.

Thanks again.

Take it and see. You'll either get better or worse.

July,

I agree! I also feel better with my methyl B12. I suggested to a friend and it made her feel terrible and anxious. So wonder what that means?