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Need help interpreting MTHFR results.
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Tick41
Regular Member
Joined : Feb 2016
Posts : 331
Posted 6/22/2017 2:13 PM (GMT 0)
This is what the analysis for me says:
"This individual has one copy of the MTHFR 677 C>T mutation and one copy of the MTHFR 1298 A>C mutation. In the general population, 19.8% of individuals are likely to have this configuration. This is referred to as a compound heterozygote. Based on this genotype the MTHFR enzymatic activity may be decreased up to 50% below normal but the individual is not expected to be at an increased risk for elevated homocysteine levels nor at increased risk for thrombophilic events."
Traveler
Elite Member
Joined : May 2007
Posts : 36573
Posted 6/22/2017 2:28 PM (GMT 0)
I wish I could be of more help, but I don't understand it well enough and wouldn't want to mislead you, so all I know to do is suggest that you go here to learn more:
mthfr.net/
Hopefully those that understand this better will be along soon to help!
Traveler
Elite Member
Joined : May 2007
Posts : 36573
Posted 6/22/2017 2:52 PM (GMT 0)
bump
afiya4health
Regular Member
Joined : Nov 2013
Posts : 196
Posted 6/23/2017 1:39 PM (GMT 0)
You'll have a harder time detoxing toxins out of your body compared to someone who doesn't have MTHFR mutations.
Therefore herxes might be longer, more intense and you should probably up your detox slightly when feeling bad (but not too much).
Immunity
Regular Member
Joined : May 2017
Posts : 51
Posted 6/23/2017 7:21 PM (GMT 0)
Hi Tick41,
This means that you are heterozygous for both of the MTHFR genes. Basically you are in the middle grounds between Normal and Homozygous (i.e. none of your chromosomes have the normal functioning gene). In other words, for both (677 C>T & 1298 A>C) you have one copy of your DNA making the normal enzyme, and another copy making the semi-normal enzyme).
In your case, supplementing with things such as methylB12 and others would be good, especially if you are chronically sick. I would pursue this genetic test by looking at how your body is doing to see if your body is not catching up with methylation demands: (measuring levels of B12, homocysteine, looking at red blood cell count and morphology, and other methylation pathway markers).
This site has a ton of information regarding MTHFR and what you can do if you are heterozygous (MTHFR.net)
Immunity
Tick41
Regular Member
Joined : Feb 2016
Posts : 331
Posted 6/24/2017 10:12 PM (GMT 0)
Thanks guys!
I was told I would need to start supplementing methyl-folate
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