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Experiences with Minocycline?

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Posted 6/4/2018 12:02 PM (GMT 0)
What was everyone's experience with mino? Did you see improvement and at what point?

I just started taking it last Friday twice a day and today I have been feeling a little nauseated and dizzy. Plus lots of fatigue.

I am planning on going to a concert tomorrow night and then to Chicago for two cubs games with my dad on wednesday and thursday. Should I keep pushing through at two a day? I am just afraid that I will feel terrible during this time that I took off work to do some fun things.
Posted 6/4/2018 2:42 PM (GMT 0)
I have been on Mino for a while, i haven't experienced any nausea or dizzyness. I do have fatigue, but have always had it.

I am taking Mino, Zithro, Rifabutin, Oil of Oregano, Monolaurin, VSL3/Florestor, Milk Thistle, NAC at the moment.

honestly feel like this combo has been a big improvement for symptom relief...going to stick with it for a while
Posted 6/4/2018 3:00 PM (GMT 0)
For me mino worked amazingly but at the start it was very hard..

I steadily declined for the first 6 weeks, visiting the ER many times. The dizzyness was one of the worse symptoms along with many other neurological symptoms. I guess I was just herxing real bad.

After 6 weeks the improvement was dramatic. I went from being practically bed ridden to back at work albeit struggling within 4 months
Posted 6/4/2018 4:23 PM (GMT 0)
I took mino with Rifampin for bart for about a year in total.


I 'lost' several symptoms on it : tailbone pain, shoulder pain, nodule on my foot disappeared, knee pain, baker's cysts (greatly diminished), swollen clavicle lymph node....

probably a few more that I'm not thinking of.
Posted 6/4/2018 4:35 PM (GMT 0)

Girlie said...
I took mino with Rifampin for bart for about a year in total.


I 'lost' several symptoms on it : tailbone pain, shoulder pain, nodule on my foot disappeared, knee pain, baker's cysts (greatly diminished), swollen clavicle lymph node....

probably a few more that I'm not thinking of.

Interesting.. I have tailbone and shoulder pain still and foot pain as well. That would be great to see those gone along with my brain fog and fatigue! Did you ever have brain fog?
Posted 6/4/2018 5:08 PM (GMT 0)

NicHostetler said...

Girlie said...
I took mino with Rifampin for bart for about a year in total.


I 'lost' several symptoms on it : tailbone pain, shoulder pain, nodule on my foot disappeared, knee pain, baker's cysts (greatly diminished), swollen clavicle lymph node....

probably a few more that I'm not thinking of.

Interesting.. I have tailbone and shoulder pain still and foot pain as well. That would be great to see those gone along with my brain fog and fatigue! Did you ever have brain fog?

I think I had worse than brain fog....my brain was awful for awhile. Short term memory was in the crapper, sometimes my husband would be talking to me and I didn't know what he was talking about (that was only a few times), i got confused easily.

Much better now. Just in the past couple of months I am now able to remember what day of the week it is when I wake up in the morning...sometimes it takes a minute or two.

my tailbone pain was really bad...and then one day, I said to my husband that it wasn't as bad...and within a couple weeks it was gone...
I still have pain around my left shoulder blade...but I also had sore shoulders - the tops not the blades (left and right...putting on jackets hurt.
They're good now.

My foot pain got better, but I'm feeling it again - not as bad...has me concerned that all this babesia focussed treatment is allowing bart to come back.
Posted 6/4/2018 8:04 PM (GMT 0)
I've had problems with numerous medicines, but no problems with minocycline to date. No side effects, not even dizziness. I've improved a lot while on protocols that include it.
Posted 6/4/2018 8:42 PM (GMT 0)
Mino makes me feel like I’m walking on a ship in rough seas. You are not alone.
Posted 6/4/2018 10:01 PM (GMT 0)
Is the Minocycline (possibly combined with Rifampin) effective at penetrating the BBB?
How long do I have to take this combo for it to get rid of the pathogens?
And should I pulse it or not? Is it just as effective when pulsed?
Thanks.

Post Edited (insomniaaa) : 12/28/2020 3:10:31 PM (GMT-7)

Posted 6/4/2018 10:47 PM (GMT 0)

insomniaaa said...
Is the Minocycline (possibly combined with Rifampin) effective at getting rid of constant headaches and severe insomnia symptoms?
How long do I have to take this combo for it to get rid of the critters in my head?
And should I pulse it or not? Is it just as effective when pulsed?
Thanks.

Minocycline is one of the better abx for penetrating the CNS. So, it should be good at irradicating what's in your brain.

I pulse. Dr. J (well-known, experienced LLMD) has all patients pulse.

But, you do want to do it on a schedule...not just willy/nilly...
Posted 6/4/2018 10:54 PM (GMT 0)
Mino is strong... i feel like an alchoholic man and my tinnitus explode when i'm on it jajajaja
Posted 6/4/2018 11:15 PM (GMT 0)

OriolCarol said...
Mino is strong... i feel like an alchoholic man and my tinnitus explode when i'm on it jajajaja

Man? lol. I assumed you were a 'she' with the Carol. (here that's a female first name)...

sorry....I'll have to change the picture of you in my head now. tongue
Posted 6/4/2018 11:30 PM (GMT 0)
Hahahahahahahahahah girlieeeee!!!!well you're not soo wrong.... unfortunatelly my girlfriend has lyme now and she reads this posts....

Oriol is my name and Carol my girlfriend's name. You re right

Jajajaja don't worry girlie :P
Posted 6/5/2018 1:43 AM (GMT 0)
After reading Dr Sapi's research I was excited to try it with pulsing tindamax but Minocycline gave me bad dizziness/ spaciness/ vertigo and I had to stop it. I was really disappointed.
Posted 6/5/2018 2:17 AM (GMT 0)

insomniaaa said...
Is the Minocycline (possibly combined with Rifampin) effective at getting rid of constant headaches and severe insomnia symptoms?
How long do I have to take this combo for it to get rid of the critters in my head?

if u've had this long enough, it has created biofilms in your brain and you cannot get rid of it there completely because effective treatment of lyme persisters with biofilms is currently unavailable.

what u can do is greatly diminish their numbers to the extent they do not bother you and u have minimal symptoms left, and wait for research to catch up in several years.

Mino with rifampin yes are among the best combination you can possibly get, they both get very well absorbed in the brain and together they form a persister treatment, meaning they are active against dormant lyme bacteria (which none of them are taken separately)

insomniaaa said...

And should I pulse it or not? Is it just as effective when pulsed?
Thanks.

the only true study about pulsing antibiotics for lyme was done on a peniciline antibiotic that has different type of action than tetracyclines (like mino)
even so, this one on a penicilin called ceftriaxone was first successful
aac.asm.org/content/early/2015/05/20/AAC.00864-15.abstract
then several months later another team released another paper showing it was not successful
/www.ncbi.nlm.nih.gov/pmc/articles/PMC5095124/

so i really have doubts pulse dosing works, but even if it does i have more doubts a tetracycline like mino should be pulsed. tetracyclines are bacteriostatic, they stop the bacteria from dividing, they do not kill it directly ... so im not sure what would pulsing achieve... the idea of pulsing is to trick the bacteria into thinking it is safe to divide, only to hit it with an antibiotic that is deadly when division happens. That antibiotic is from penicilin class and NOT a tretracycline...

Anyway, i know Girlie used to pulse it so she can tell u more.

Post Edited (mpost) : 6/4/2018 8:21:55 PM (GMT-6)

Posted 6/5/2018 2:48 AM (GMT 0)
mpost - one of the reasons Dr J has patients pulse the abx is to allow the immune system to kick in.
Minocycline is one of the abx he uses with success.

He has been treating Lyme for many years now and is as successful as other llmd’s at getting his patients in remission.

I believe it was Dr. Burrascano who pulsed when he self-treated and was successful.

How do you know that you can’t get the persisters out of the brain?
There are people who achieve symptom free - not left with minimal symptoms.

Ceftriaxone is a Cephalosporin
Posted 6/5/2018 10:19 AM (GMT 0)
John Fisher smith achieved the complete remission (the ranger that appears under our skin), but he was continually treating for 8 years with ceftriaxone ...

I have many doubts myself. Today I have started a pulsed treatment of cefotaxime and I am afraid that it will be a failure ....

Based on the theory that the oral abx and the iv are equally effective ... I am walking on a tightrope. I'm doing it because acording to mi llmd acute problems are resolved faster with intravenous treatment, like bell plasy, polyneuropathy (what i have) but if polyneuropathy is secondary to a high colony of biofilms does it mean that i will never cure it? it's soo complicated... TT

According to what I have been told by some microbiologists by mail, persistent, biofilms etc ... they are not a problem when they are continuously treated 24 hours a day with antibiotics ... it can take more or less to kill the persistent but eventually they will fall.

Attention, I am not affirming anything ... I simply show here what I have been told.

I do not know if they are wrong or they are right.

Post Edited (OriolCarol) : 6/5/2018 4:27:21 AM (GMT-6)

Posted 6/5/2018 10:22 AM (GMT 0)
Have they done any studies about persisters in test tubes, attacking them with abx for 3 or 4 years, to be able to claim that they can not be killed?
Posted 6/5/2018 11:37 AM (GMT 0)
Are you pulsing only cefotaxime? One reason for combining several antibiotics is that it is believed to help prevent resistance.
Posted 6/5/2018 11:38 AM (GMT 0)
But i'm pulsing it for lyme Dahlias. It doesn't create resistance. If it create resistance like staph, strep etc... we would be all dead
Posted 6/5/2018 11:45 AM (GMT 0)
I take it for Lyme too, and that's what my LLMD told me. That's not the only reason they pulse, but it's one.
Posted 6/5/2018 11:54 AM (GMT 0)
Have you had a good experencie with cefotaxime Dahlias?
Posted 6/5/2018 12:11 PM (GMT 0)

OriolCarol said...
Have you had a good experencie with cefotaxime Dahlias?

No, I'm allergic to cephalosporins. My doctor wanted me to take Cefdinir or Ceftin with the minocycline as part of a larger protocol, but I couldn't take that one.
Posted 6/5/2018 12:21 PM (GMT 0)

OriolCarol said...
John Fisher smith achieved the complete remission (the ranger that appears under our skin), but he was continually treating for 8 years with ceftriaxone ...

I have many doubts myself. Today I have started a pulsed treatment of cefotaxime and I am afraid that it will be a failure ....

Based on the theory that the oral abx and the iv are equally effective ... I am walking on a tightrope. I'm doing it because acording to mi llmd acute problems are resolved faster with intravenous treatment, like bell plasy, polyneuropathy (what i have) but if polyneuropathy is secondary to a high colony of biofilms does it mean that i will never cure it? it's soo complicated... TT

According to what I have been told by some microbiologists by mail, persistent, biofilms etc ... they are not a problem when they are continuously treated 24 hours a day with antibiotics ... it can take more or less to kill the persistent but eventually they will fall.

Attention, I am not affirming anything ... I simply show here what I have been told.

I do not know if they are wrong or they are right.

How do you know that Smith was on ceftin? And if I recall correctly in essence he pulsed because every time he would try to stop abx he would relapse within a week or two and go back I them.
Posted 6/5/2018 12:28 PM (GMT 0)
Because He says it in some articles.

but he wasn't on ceftin (cefuroxime), he was on ceftriaxone.

it's what he said: I'd been infusing myself with intravenous Rocephin every day

And i have a friend that lives in EEUU that talk to him about it. But you're right he pulsed. I want to say that he was treating constantlly, during 8 years (pulsing etc... but nonstop)

Maybe i'll do myself the harakiri because now the most frightening symptom that can have has dissapeared... waking apneas... and if it return with cefotaxime.... but well.. we'll try...

Post Edited (OriolCarol) : 6/5/2018 6:45:14 AM (GMT-6)

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