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Doxycycline and Flagyl

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Posted 5/12/2014 2:27 AM (GMT 0)
In March - i convinced my doc to give me three weeks of Doxycycline 200 mg per day - thinking that I may have Lyme disease. Near the end of the third week I started to feel a bit better for a few days...but then that ended and it got worse again. But, i have had periods of good days before anyway.

A week ago - my Doc gave me a week of Flagyl 500mg X2 daily because of a bacterial infection that showed up from my pap test. (I had also show white blood cells in my urine previously) This is the only thing that has shown up with all my extensive imaging/blood work, etc.

I finished the Flagyl yesterday.

Just wondering - if I do have Lyme, would the antibiotics I took help it or was it too short a time to do anything?
Posted 5/12/2014 3:20 PM (GMT 0)
no one has responded.... :(
Posted 5/12/2014 3:56 PM (GMT 0)
No that's not near enough time to take abx for Lyme plus Doxy at 200 mg. is too low of a dose to do much of anything.

My first doc gave me that dose and I felt nothing but did have some herxing when I upped it to 300mg. (couldn't tolerate 400mg. because of the nausea). 200mg. treats an upper respiratory infection, not Lyme.

Have you been to an LLMD yet to get tested through IGeneX?
Posted 5/12/2014 5:55 PM (GMT 0)
Thanks for that info.
I am waiting for test results, but the ones I get covered under my medical plan here are usually a waste of time...but I thought I'd go that route first - maybe it'll show positive and I can begin treatment.

We don't have any LLMD's here (BC Canada) - but there is a ND close to my home that isn't LL, but will do the Igenex testing. She is willing to treat with antibiotics and has been to a workshop on Lyme disease. So, as soon as I get the results from the "free" Lyme test, I will determine whether I need the Igenex testing.

My doc has been pretty good, so far...I've been unwell for a year now, and she has tested me for just about everything under the sun, as well as a scan of my adrenals, barium swallow xray, MRI of my pituitary, MRI of my cervical spine and has now referred me to an ENT to look into the lump in my throat and my gagging at night while trying to sleep....jeez - what I friggin mess I am.
cry
Posted 5/23/2019 1:46 PM (GMT 0)
I would think that you should feel change with antibiotic treatment.

I am in a similar boat. I am now on week six of doxycycline 100mg 2xday. For me though, it has made a significant difference. The first week or so I felt worse than I have ever felt, but then it was amazing how I started to feel almost back to somewhat normal,,,,maybe 80 percent. I went from barely being able to function where I could hardly walk normal and thought I was going insane, intense nerve firing and deep pain, fatigue, etc etc etc to having minimal pain and having energy again--enough to even golf!
And I cannot afford LLMD or non insurance treatments, and now I wonder where I go from here. My dr. is doing 8 or 9 weeks of doxy.
BUT my point is this. I have been going through this for over 20 years and I kept saying I thought it was Lyme. But diagnosed with all the other wrong things, RA, Fibro, etc etc and ONE DAY I had a bacterial infection so they put me on FLAGYL and it was life changing. I finally for the first time in 20 years had NO pain. whatsoever. This made my doctor suspect lyme and going through all my millions of dr appts and symptoms determined chronic lyme and now I am on doxy. I need more than this.
CAN I DO DOXY AND FLAGYL AT SAME TIME???
Posted 5/24/2019 6:33 AM (GMT 0)
You sure can. Antibiotic combos are not uncommon, actually the preferred treatment..I've heard of Minocycline and Tindamax (Tinidazole) and also Doxycycline and Flagyl (Metronidazole). I did Minocycline and Flagyl (generic Metronidazole) and it was intense. Waiting for an opportunity to treat this way again. There are numerous abx combos that include many different mechanisms of action.

And it's not unusual to feel 5-10X worse while you Herx. My most recent Herx was from an herbal plant I bought from grocery store (actual Oregano plant whole), it was dying so I put the leaves scrunched up in some sweet potato mash, and it must have killed some things because I was hurting, the dose was a little too much as I got bloated and gassy with kidney pains similar to when I eat too much raw garlic at one time.

There is some question as to whether 100-200mg twice daily Doxycycline is too bacteriostatic (doesnt kill only stops reproduction) and if 200-400mg taken orally reaches bactericidal blood serum levels, hence the more spendy IV abx that reach greater concentrations in the blood. I took 200mg of Doxycycline on an empty stomach and vomited, it is sorta rough on the GI tract.
Posted 5/24/2019 6:57 AM (GMT 0)

lamazak said...
I would think that you should feel change with antibiotic treatment.

I am in a similar boat. I am now on week six of doxycycline 100mg 2xday. For me though, it has made a significant difference. The first week or so I felt worse than I have ever felt, but then it was amazing how I started to feel almost back to somewhat normal,,,,maybe 80 percent. I went from barely being able to function where I could hardly walk normal and thought I was going insane, intense nerve firing and deep pain, fatigue, etc etc etc to having minimal pain and having energy again--enough to even golf!
And I cannot afford LLMD or non insurance treatments, and now I wonder where I go from here. My dr. is doing 8 or 9 weeks of doxy.
BUT my point is this. I have been going through this for over 20 years and I kept saying I thought it was Lyme. But diagnosed with all the other wrong things, RA, Fibro, etc etc and ONE DAY I had a bacterial infection so they put me on FLAGYL and it was life changing. I finally for the first time in 20 years had NO pain. whatsoever. This made my doctor suspect lyme and going through all my millions of dr appts and symptoms determined chronic lyme and now I am on doxy. I need more than this.
CAN I DO DOXY AND FLAGYL AT SAME TIME???

Hi lamazak - that post was from 2014 - funny to see one of my first posts on the forum.

I believe doxy and Flagyl can be taken together. I currently take mino and Flagyl

It will be difficult to get a non lyme doc to prescribe you the abx that is needed. It takes many months to years to treat these infections.
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