Disulfiram - Part 11

Aerose91 said...
Is this length delay normal for disulfiram? I've been on it a couple weeks and haven't noticed anything yet

The side effects of the disulfiram (cyclothymia, weird dreams, smell) happened very quickly. The herx took a week or two.

Aerose91 said...
Cool. Thanks. I'm looking forward to a herx!

Same here lol. I hope to God it's over quick and that I feel more human afterwards!

So I’m on day 2 of low dose and I also took hydroxy-B12 as well as Zinc and the twitching and muscle fortified is back. Fog and pressure is very low which is the worst symptom so I’m very happy.

Just wondering why the muscle tightness/twitching. Zinc and B12? Pain in my chest as well. Obviously this is all some type of herx but never happened before so I wonder if the B12/Zinc did something?

🔹RainyCloud said...
Hi disulfigang.

Good news.

I got an email back from Torrent Pharma about in inactive ingredients in Esperal 250mg.

I believe they accidentally sent me a little too much information, and I'm a bit confused how to read the string of images.

https://ibb.co/album/ktz1aa

That seems normal enough. All the same ingredients are in my serrapeptase, and most other supplements. Most of them are anticaking agents and fillers, like magnesium stearate. Nothing unusual here, fortunately.

🔹RainyCloud,

I know it's rough right now. Please consider backing off the disulfiram. It's a rough ride with lyme and I know you haven't had life easy either. You're tough, but please, we all need to take breaks sometimes.

It sounds like you might be at risk of the psych issues mentioned at the higher doses. Especially with the antidepressants you said you're on, along with the aderall.

Please don't burn yourself out. This stuff is showing so much promise.

steelogreens said...
So I’m on day 2 of low dose and I also took hydroxy-B12 as well as Zinc and the twitching and muscle fortified is back. Fog and pressure is very low which is the worst symptom so I’m very happy.

Just wondering why the muscle tightness/twitching. Zinc and B12? Pain in my chest as well. Obviously this is all some type of herx but never happened before so I wonder if the B12/Zinc did something?

The amount of zinc needed to disrupt copper absorbtion is much more than the average 50mg. Are you sure it's not just a herx? How good is your detoxing? I get twitching as well but it's shortly after dosing which makes me think that it's die off.

B12 is not dangerous in excess.

And I do have Bart, but again, nothing like yesterday when I took zinc did I get those side effects. Was so in uncomfortable.

JovaLyme said...

steelogreens said...
So I’m on day 2 of low dose and I also took hydroxy-B12 as well as Zinc and the twitching and muscle fortified is back. Fog and pressure is very low which is the worst symptom so I’m very happy.

Just wondering why the muscle tightness/twitching. Zinc and B12? Pain in my chest as well. Obviously this is all some type of herx but never happened before so I wonder if the B12/Zinc did something?

Do you have Bartonella steelo?

I have these symptoms too (twitching, chest pain etc) and they have worsened since taking disulfiram.

I think there might be something in what Quin says about disulfiram stirring up Bartonella, but not killing it and you might need to add a Bartonella med to the disulfiram to deal with what could be Bartonella symptoms.

It doesn't look like disulfiram does anything for bartonella from what I can tell, so if you are using it as a monotherapy, you could just make your bartonella symptoms worse or wake it up. That's what I think disulfiram has done to me.

Also, I read a study that said taking zinc can potentially make any copper deficiency worse and disulfiram chelates copper, so that could be part of your problem. Maybe try laying off the zinc and see if your symptoms improve?

Thanks Jova.

I’m almost certain it’s the Zinc. I guess since I don’t get much neuropathy, no point in me taking it and it negatively impacts my herx with the DSF. So many guesses haha.

It’s alright. It’s a little better this morning and it will be out of my system in a bit.

Sucks that we are trying to find things to help and sometimes they can have adverse effects and can really be uncomfortable. Last night was horrible

UnsightlyCignet☄️ said...
steelogreens

I've literally been having raging herxes, literally punching cupboards herxes because of the brain inflammation.

This disease is so awful. I've got to laugh, but Turmeric knocked it down dead but oh man it's horrible.

Got a round of detoxing and brain herbs coming in soon. Hoping this eases the pain lol

The head stuff has died down big time for me. So I think give it a bit of time and it will pass. Now is a question of how darned long do we have to be on it and it what does to be sure it’s gone lol. Just a big guessing game. I’m seeing a new specialist who is an internist so let’s see what they have to say.

Forget about the other side of the equation which is the mental part of getting back to normalcy and not being terrified the symptoms will come crawling back lol.

steelogreens said...

The head stuff has died down big time for me. So I think give it a bit of time and it will pass. Now is a question of how darned long do we have to be on it and it what does to be sure it’s gone lol. Just a big guessing game. I’m seeing a new specialist who is an internist so let’s see what they have to say.

Forget about the other side of the equation which is the mental part of getting back to normalcy and not being terrified the symptoms will come crawling back lol.

You're telling me. I'm just gonna pray and hope for the best here. Hope your internist can help you out.

oregonhay said...

I had a massive, what seemed like 24 hour hangover Sunday-Monsday. Then some kind of miracle happened and the the hangover supplements-- Dihydromyricetin and Taurine and came in the mail, I took that. Hangover went away. But I still had the soreness , aches and pains -- everything but the hangover. So I took L-Glutamine and Creatine. That helped 2-5%. Then I had the 'restless leg syntoms'. I took Quinine for my legs. That helped another 2-5%. And I took 2x Naproxen that helped 2-5%. Slept, and now I am back to reality. Wow it was harsh. Still a little spaced out. I am still at 250mg but thought about going to 125mg. I am going to stick with 250mg for now. MAYBE I might try to trigger another 'boomerang' -- it comes down to pulsing. So apparently you can pulse Disulfiram in mid treatment and it has a multiplier effect.

That sounds horrible and funny at the same time. Insight after insight into what does what! I hvae my detox supplements coming this weekend. Until then I have Turmeric and bicarb soda.

There's no way I'm exceeding 250mg. I think that's my maximum.

I am on my second attempt. I took it for about 5 weeks and stopped for a new job. I had delayed herx during a 3 week break from that one.

Now I am on my second attempt, perhaps week 7 or 8. 62.5 3 weeks, 125 3 weeks, 250mg two or three weeks. Was about to go to 500mg but who knows. Maybe I should stay at 250mg and take 3 day breaks. Because if that causes a delayed herx and I'm able to get the lyme out and hit it, that's moving forward. I was even thinking going to 500mg .. every other day. Or 750mg every 3-4 days. The first idea is effectively 250mg a day but maybe-sort-of causing a break/pulse, and therefore delayed herx, kind of ironing out the bubbles. Maybe some doctor will pick this up and try this slight change to the protocol.

oregonhay

I'm backing off right now if I'm honest. 1 week at 187.5mg and I'm having the most brutal rage attacks.

Praying that the CDC ******s have a nice place with their names on it in the lake of fire.

I'm only using alka selzer for now. I'm using the buhner herbs, japanese knotweed, Gou Teng, salvia and some turmeric.

It's definitely the DSF. I'm taking it back down to 62.5mg tonight. I'm worried as hell but I'm sure I'll be okay.