Notime4lyme said...
I just don't know why bartonella is so hard to get rid of.
Biofilm...
If it was just bartonella itself, it would be a lot easier to get rid of... But when spirochetes are pumping out biofilms, there's a protective layer that all the pathogens can hide under, why I suspect it's whack a mole with some of us who have all 3 B's...
Add in Stevia to Disulfiram or another biofilm buster, you'll see how the herxing raises tremendously, at least did for me.
Add in biofilms and persister cells, along with two other coinfections, you have one chronic infection that's very hard to get rid of. While you suspect you're dealing with bartonella, believe me your not, many things at play why many of us are staying sick.
Photo of what biofilms look like
https://www.frequencyfoundation.com/2017/01/12/biofilms/You use a drug like disulfiram or an antibiotic, you kill off a small portion of the biofilms and spirochetes and bartonella bacteria cells, then feel a herx. So on and so on, a lot of us have been doing this for almost a decade, it feels never-ending due to the biofilms and persister cells.
Everyone with lyme seems to have mucousy like texture in their mouth and back of there through, my suspicion is, this is one of the major signs you're infected with lyme. I had never had any mucous problems until I was bit by a tick. Mine has thinned out after 9 years being on antibiotics, it really thins out when I'm on Disulfiram. My suspicion is, once you get target enough borrelia persister cells spirochetes that are shedding these biofilms, this protective layer will keep coming down with time, if you're not reaching these dormant hiding round body forms, your chance of remission is very slim. Disulfiram along with a few other new drugs I think is giving many of us a fighting chance due to it's long half life, penetration deep into tissue along with the brain, amongst other things it does like waking up dormant cells.
Pyrazinamide helped me the most with bartonella, paired up with doxy and I tried it little with rifampin. Helped me tremendously lower the bartonella psych symptoms.
My personal feeling is, I think it's smart to rotate between Disulfiram and an antibiotic. Kind of like what they were planning to do with Disulfiram for AIDs patience.
"Disulfiram can "wake up" latent HIV to be killed, study finds"
https://www.consultant360.com/story/disulfiram-can-wake-latent-hiv-be-killed-study-findsDisulfiram for whatever reason pisses off dormant cells in viral form, bacterial form, and probably even in other forms like cancer. What Scientists and Doctors were planning to do, is wake up the HIV virus cells with Disufliram, then follow up with an antiviral drug. No reason why you can't do the same thing with Chronic Lyme Disease!!!
I suspect those that are expecting a miracle with just herbs and antibiotics, just never going to happen in my opinion. First herbs don't pass the brain barrier enough, nor do they penetrate deep enough or half a long enough half life. And considering Disulfiram seems to be like drawing these dormant persister cells out of hiding, may be the key we need for a cure.
Using something like Disulfiram for a month, then following up with azlocillin, may be a popular protocol in the sometime future.
https://www.medicalnewstoday.com/articles/lyme-disease-treatmentProblem now is, for some of us, it's not a matter of finding a drug that's going to kill enough of the dormant persister cells, but actually being able to tolerate the die off. The die off from Disulfiram is so tremendous, easily put a chronic lyme patient in the hospital, along with give them psychosis from the die off in there brain, which many are reporting on the Facebook group page. My personal opinion is, the psychosis has nothing to do with the side effects of the drug, but the tremendous die off. I know from experience, because when I first got on Disulfiram, I had small pyshsosis sympotoms flaring, similar to when I was on primaquine, when I increased the drug dosage they increase, when I lowered the dosage, they dissipated. After 5 months, now I can go on 250mg and not get any psychosis like symptoms. Some would say I have built up a tolerance, doubtful, as I have been rotating between disulfiram and antibitoics like pyrazinamide. I had the same psychosis like symptoms flaring when I was on three antibiotics at once, along with pyrazinamide at times. It's amazing how one drug like Disulfiram can be just as powerful as three antibiotics used at once against lyme, that's how it compares in my personal experience. Explains why Dr. Rajadas said it could win the molecule of the year award. My personal feeling is Bartonella die off is the primary cause of the herxing psychosis. It's a harsh bacteria, I really don't think borrelia nor babesia causes the amount of neurological problems as bart. Bartonella is also a huge reason why so many have epilepsy seizures... After I finally hit my chronic lyme with a big gun like primaquine, it wasn't until that time I finally got a taste of what it was like to deal with a lyme like seizure, not fun, feels like you're going to die. Ever since taking primaquine, my bartonella has been wide awake and I seem to be out of that autoimmune phase of constant fatigue and tiredness. Now I feel so much better, but still killing of bartonella cells and spirochetes now on a daily basis. After dealing with this disease for almost 10 years now, I really have started to really understand more and more how some of the top Lyme Doctors comparing it to peeling back layers of an onion, the layers I think are just a direct relation to the biofilms.
I really like what Dr. Tania Dempsey said about
chronic lyme, I'm paraphrasing, but she said something on the lines that bartonella shouldn't really be called a coinfection, but instead one of the primary infections. As it's one of the hardest obstacles to overcome... Coinfections have been underplayed big time.
https://youtu.be/937sZJDNVGw
Even Dr Kinderlehrer recently stated that he thinks Bartonella is the hardest to treat...
https://youtu.be/q6dlpvbuxrq?t=1152And I really think the majority of lyme patients, especially in early stage, don't realize they are infected with bartonella. For some of us, it doesn't show it's face to years down the line, then the symptoms come out of nowhere and flare up. Very sinister bacteria that can remain dormant, put you in some type of autoimmune state, and if you don't ever target it, probably be sick for the rest of your life. May be an underlying cause for many people with mental illness and even things like hypothyroidism and hyperthyroidism, aka Hashimotos and Graves, listen to this great episode with Dr. Hirsch
https://youtu.be/tgjjtdapfdi?t=916My personal feeling with the medical community is, they don't want the truth coming out about
this bacteria... Like Ed Breitschwerdt, we should of been at the tipping point years ago... “I believed we would hit a tipping point two years ago with this.” Instead the medical system would rather treat the symptoms, rather the source of the problem. "Big pharma is not in the business of curing, but disease management and symptoms maintenance" - Pharma Rep Gwen Olsen
https://www.northcarolinahealthnews.org/2013/12/05/bartonella-is-everywhere-so-why-dont-we-know-more-about-it/Post Edited (Charlie55) : 5/18/2020 2:17:23 AM (GMT-6)