Methylene Blue for Bartonella

READ BOTH POSTS PLEASE

Hey guys.

Seeing as we have a thread for Disulfiram, I thought I'd create one for methylene blue.

I have been inspired, by the posts on facebook. One in particular of an individual who has regained a great deal of autonomy having used the two in conjunction, with suspected bartonella and lyme to name a few. The guy is a student and is making progress with little support from his family.

I am beginning today, to use methylene blue as a monotherapy. Until I get my antibiotics, where I will use it in conjunction with them as well.

I'm starting on a dose of approximately 50mg. Just to test the water and I aim to take 800mg for a week straight to see it's effect on bartonella. After steadily increasing.

Here's a document with information based on it's historical use as an antimalarial. Along with information from the John Hopkins studies done last year.

Methylene Blue for Bartonella

Here also are one individuals experiences using methylene blue. He has been very thorough. There are others that have experienced improvements, but not total cures so there's a way to go, it being experimental and all but I have hope.

Facebook Success

It's available in 100mg caps from a compounding pharmacy if you're in the US. I am however, buying my own powder and making my own capsules, with the help of a scale. The powder is cheap - but not "pharmaceutical grade" it has been tested and is practically identical in quality of the MB used in a clinical setting, be it IV or orally.

Here are the test results on the MB in powder form from APC

A risk I'm willing to take in all honesty, considering how disabling this disease is.

MB has been used for over 100 years. It should be taken with food, to avoid GI complaints. It also colours urine a vivid blue., and my cause minor bladder irritation.

I will post additional studies in a moment...

Hello Cignet

how are you getting on with your methylene blue trails ?

i came to a similar conclusion of its potential usefulness by a different route but the recent study discussed here specifically tested MB as an anti-persister drug for Bart and found it one of the most effective in the test of 100's of compounds

i then remembered that Horowitz was using it in his dapsone trials ( although for a slightly different primary purpose - to prevent oxidation of hemoglobin) this proved it could be taken orally.

did you have any success with treatment?

did making your own capsules work OK for absorption - or do the compounders add something else?

Post Edited (Garzie) : 10/20/2020 2:47:38 PM (GMT-6)

Hi, I'm new here.
about 6-8 weeks into Methylene Blue treatment at 400mg MB/day+ was the last time I felt the pain that had originated 9 mo prior, down my neck and into my hands and feet. By the time I started treatment the pain had settled in like arthritis. Glad to report: No more stiff shoulders having me feeling like I'm sleeping on both of them wrong and hands that lose their limber. I still don't know if this pain was was bartonella that came back or borrelia I keep testing negative for, but it seems to be gone due to MB. I'm continuing treatment another 6-8 weeks.
You need a strong stomach to take MB. It also makes me more fatigued and my herx includes a sore throat. But upon ramping up, I feel antidepressant and stimulant affects which I appreciate. I haven't experienced serotonin syndrome from MB like I did from tricyclic antidepressants, but can feel the possibility.
I found a place in FL for about $3-4/pill infuservamerica. My Dr started me off at 50mg 2x/day. Because each cap is so expensive, I would advise pre-planning your availability of 50, 100, 150 and 200mg capsules with ur doctor. I ramped at rate of about 50mg/week. When I hit 400 faster than that my kidneys and liver told me that was a bad idea. At 155lbs (50yoF), 400mg is min effectivity threshold. I was only able to tolerate up to 500mg/day alright, but have settled on a max of 450/day= 3x150mg. My head feels like it's going to explode with more than that and I'm left wondering if that's herx or damage. So I obviously gave up on the 700mg/day 1 week regimen I initially planned and opted for traditionally longer treatments needed with late stage Lyme infect's.
I've had Lyme 40 years this spring... Officially went septic with endocarditis in 2017. My heart had been having intermittent attack sx from Bartonella until an LLMD saved me. Mainstream medicine could drain the infection but not test it for pathogens (like how they diagnosed me with brain disease from a (Lyme) pathogen, yet no efforts to figure out which one). Rifampin saved my life but I grew an intolerance which caused a single pill to fail my kidneys last year when I tried again to complete treatment. So Methalyne Blue sounded great. It seems effective and safer than most and is also kinda helpful against malaria (babs) and borrelia. I Initially Paired with azithromycin.
Good luck!!

Post Edited (SC Gal) : 4/10/2021 5:41:31 PM (GMT-6)

Hi, thanks for the welcome! I'm in Santa Clara CA. I was infected in the East Bay area in 1981 when I was 10. Bart Sepsis/Endocarditis 2015-2018. Found Babs 9 mo ago. I am pleased with Frontier Medical LLMD in Bay Area here, but, even then, have to work at this and really hard for a sick person. I have been bedridden and active several times in past 30 years. It's going to be a summer to celebrate once we get through all this!

Post Edited (SC Gal) : 4/10/2021 5:44:13 PM (GMT-6)

interesting Cignet - thanks for the info - sounds like a pharma-grade source - could you pass on the supplier - I am in the UK also

thanks for the info Cignet

i am also self-treating and was interested in MB at some point provided i could find a source i felt sufficiently comfortable with.

the one i was looking at is here
https://www.ebay.co.uk/itm/25g-Methylene-Blue-Crystals-granules-fish-infection-indicator-dye-free-P-P/140667091593?epid=1622857283&hash=item20c0697a89:g:nrkAAOSwUdlWgVUj

but i think its different from the one you linked to - I wrote to the seller in the link i posted asking about the grade of the MB they were selling - but they did not respond so i assume that one is not pharmaceutical grade.

any chance you can point me to the Facebook post with the testing of the one you linked to - would be very interested in that.

i know what you mean about the quality of LLMD's in the UK - i found several that would happily take my money - but i didn't feel they knew any more about it than i did - so decided i would do better using that money for treatment than consultations

thanks again and wishing you every success with the abx combo

got it - Thanks Cignet - you too!

I'm convinced to buy this without an Rx if I can find a reliable source that ships to California. Unfortunately this UK ebay link couldn't. FB group I found wasn't helpful. Anyone?
A European company patented their process for making a really pure product about a decade ago but doesn't seem to sell direct. So is all the hype about getting only the purest of product really essential or a ply to increase rx demand? I have found a few USP offerings on Amazon, but at steeper prices than my rx. I bought the higher quantity bottle from BioPure without noticing that the product label dropped to Lab grade. I'm wondering if they have one process with two labels for marketing purposes. Even with the bottle here I just don't think I'll chance it because I don't want to wonder if I had done myself harm.
More MB side effect feedback: It seems helpful in quelling the brain infection burrowing sensations with a welcome slight mood lift. But it causes overall brain pressure feeling and increases Lyme brain foibles. Occasional back pain followed by UTI sx of pain and urgency, insomnia, fatigue, thicker brain fog. Glad to report that my kidneys are holding out fine after an intermittent jolt. I'm getting regular blood tests that show strain but nothing serious. I wrote above how it's cured my pain/arthritis.
But it's not really helping my brain infection so I'm pairing with artiminisen and will switch to malarone if it's helping for babs. Or scrap that plan and treat for borellia. Wish I knew which will work.

Post Edited (SC Gal) : 4/10/2021 6:16:34 PM (GMT-6)

Hello, I'm new this blog stuff. Cignet - Could you send me a link to where I can purchase the Methylene Blue you refer to? I use Methylene Blue in my lab for various things and am about to spend money to have heavy metals test performed on the Lab Grade MB from Spectrum Chemical when I ran across these posts. I need the MB for a specific reason as you will see below.

My background is working with large volume chemical byproducts and trying to turn trash into treasure. A lot of my work in the last 5 years has been with organic acids and unique industrial uses. On March 15th, 2020 my wife of 41 years was diagnosed with ovarian cancer. The first time she ever had to go to the emergency room or a hospital stay. Through a long process it was determined that her particular cancer can be treated with anit-parisitic medicine like Ivermectin, MB, etc. This has led to extensive research on my part as well as several colleagues around the country that I called on to help with my thought process. It is becoming a general consensus among Intergrative Doctors that our present Cancer "Pandemic" may be caused by Lymes Disease that may be tied to our DNA and passed down generationally.

My wife's particular version of lymes was named after the old researcher who is the central character of this book. I must warn you, what you will read will scare you as it deals with Lymes disease as a Bio-weapon from the 50's

In the course of my research I also developed a protocol using DMSO (DimethylSulfoxide) for help with neuropthy during Chemo. It seems to have worked since she has never had a problem with it in either her hands or feet.

If anyone has interest in this I would be glad to share what we were doing. It is not expensive and easy to try.

I'm also well versed in Vitamin C IV's along with Magnesium Chloride and MSM to build the immune system. All of these diseases stem from an immune deficiency.

Polymath, you are welcome to my sealed bottle of BIOPURE Meth Blue purchase to investigate purity. I'm in South Bay area California. I hope you find it helpful for your wife. Garzie, let us know how it works for you!
I updated my earlier posts to share that I'm tolerating MB well at an ave of 400mg/day. Although it hasn't helped my brain fog, I can state that after 6-8 weeks my nuero /arthritic like pain has abated.

Post Edited (SC Gal) : 4/10/2021 6:40:50 PM (GMT-6)

Hey Polymath Science, I was wondering if you could share your protocol for neuropathy? Very intrigued

Also, are you saying its lyme or a parasitic infection that causes this specific type of cancer? Because youre talking about using ivermectin to treat it, makes me think its parasitic?

Post Edited (dcd2103) : 4/12/2021 8:48:18 AM (GMT-6)

RE: Neuropathy

DMSO Mixture for application to hands and feet to help mitigate neuropathy

Mixture by Volume:
25% DMSO (99% Pharma Grade DMSO) Purchase on Amazon
75% Distilled Water
To make less than a liter (1000ml) add 200ml of 99% DMSO to 600ml Distilled water. Stir
Topical Application:
• Caregiver: Put on nitrile gloves, then wash hands/gloves with clean water. Dry with Paper towel.
• Spray feet, legs, hands lightly with MgCl (see below) and rub and spread to thin layer, followed by DMSO over the MgCl
• When finished, rinse gloves in tap water and dry with clean paper towel.
• Keep gloves, they can be used for several weeks.
________________________________________
Magnesium Chloride (MgCl) application

• Apply MgCl as received from supplier to a small area to make sure skin is not sensitive to full strength. If not sensitive (will appear to make skin irritated), use as is. If sensitive, dilute 50/50 with distilled water and apply 2-3 times per day.
• Apply at least 2 times per day along with DMSO over large area of skin. Feet, legs, hand and arms.
• Apply with DMSO (see above)
________________________________________
Effects of treatment
DMSO is a solvent, therefore the need to make sure everything is clean. It is a vasodilator (increases size) of blood vessels to blood, etc. can be transported many times faster.
The theory is radiation and Chemo drugs once they have run the course in the body tend to collect at the extremities, i.e. feet, hands, top of head. By using DMSO, chemo/radiation that collects in the extremities after it has run its course through the body is encouraged to move back up into larger blood vessels and into the liver via vasodilation so the liver can more easily remove and detox the body. If the remnants of chemo/radiation can be removed, it stands to reason this technique may mitigate nerve damage in the extremities.

The thought came to me several years ago when formulating a product for horses hooves. If you're not familiar with horses, they have a "pump" at the base of their hooves that assists in pumping the blood back up the leg into the main body of the horse. This is why if a horse can't walk for several days they will go lame, because the body pools in the legs and the low oxygen causes a lot of problems.

The same may be true with Chemo and other drugs that go to our human extremities. If there is not enough physical activity to keep blood pumping back to our torso, then the resonant time may cause nerve damage. DMSO, a vascodilater (increases blood flow), thus allowing the chemo little time to sit in the extremities. A lot of conjecture, but I know something kept my wife safe. We were applying 2-3 times per day following each Chemo.

Oncologist couldn't believe she didn't develop neuropathy, and he never asked if she might be doing something that affected the result. He also couldn't believe her magnesium stayed high (below a certain number and they won't administer Chemo). He never asked what she might be doing, he would simply mumble to himself, "Must be something she's eating". Of course, she never volunteer anything, because he would have laughed at her and told he to stop.

By the way, if you do this, wait 24 hours after chemo. DMSO tends to destroy (oxidize) chemo so it is not effective.

Remember that you should use your best judgement and ask a medical professional before using anything found on the forums for personal use.