Waking up stomach in knots?

Are you taking antibiotics, natural antibacterials or anything else?

I wake up with actual muscle knots in my stomach area. I can feel the muscles tightening and spasming with my hand resting on my abdomen. Is this what you mean? Muscle and nerve issues in the abdomen can be intense enough to bruise or inflame your internal organs as well. I was wrecked by this for months about a year ago until I figured it out. Happy to elaborate if this sounds like what you have going on.

I managed this with stretches and attention to posture. There are some yoga poses commonly recommended for gallstones that I did twice per day, plus some other stretches for that area of my abdomen, especially before bed and first thing in the morning. Throughout the day, I noticed that I crunched my abdomen in that area and often held tension there, so I made sure to breathe deeply into my belly and sit differently, especially with my laptop. There was no easy fix, just basically a physical therapy approach. It's a super annoying problem that can cause a surprising amount of pain!