Antibiotics can poison you, know your SNPs

Was the Dr. J protocol the first ABX protocol you had done for Lyme? And how long was it on the protocol before you noticed the effects?

How can you tell by the genetic testing if you have low SOD and glutathione production?

bactrim did a number on me . mild sjs = major nerve damage . during the gulf war they didn't know if the syndrome was the mycoplasma or the prophylactic abx causing symptoms....genetic study prior to incident may have helped reveal sulfuration issues...hindsight is 20/20

JMF84 said...
Was the Dr. J protocol the first ABX protocol you had done for Lyme? And how long was it on the protocol before you noticed the effects?

How can you tell by the genetic testing if you have low SOD and glutathione production?

I had done antibiotics before with an integrative doctor, it was treatment based on symptoms rather than a set protocol. The warning signs were new fatigue - not much to go on - and a mild burning in my forearms like they had been overworked.

With Cipro the first warning was post-exertional malaise and heat intolerance. A week after completing that first treatment cycle, tendinitis began in my heels, then worsened despite discontinuing the drug. This was IV treatment and I was detoxing with two liters of saline a day, with a high rate of infusion, if it made any difference I don't know.

With genetic testing, you'd get a report showing which SNPs you have, and if they decrease SOD and glutathione levels.

agifia said...
wow this doctor poison you, what is it that you mean he is not aware of risk?
i am so sorry to hear he did this to you.

If the doctor had known about my risk factors for detox, he wouldn't have prescribed Cipro. This knowledge isn't making its way through the Lyme community and to LLMDs. I did know that fluoroquinolones were dangerous, I thought that having IV fluids would prevent toxicity, but it didn't.

bluelyme- Bactrim can inhibit folate metabolism, amongst its other risks. Medicine isn't personalized yet to predict these reactions, doctors prescribe drugs based on averages and hope for the best. After my experience, I'd recommend people use herbals if they have a lot of unexplained sensitivities, it's not worth the risk of disability by taking pharmaceuticals.

WalkingbyFaith- There are other labs than 23andMe for genetic testing of these SNPs, this one is $200, plus the cost of the practitioner. With those sensitivities and such low glutathione, I would consider looking into it.

dcd2103- This is inflammation, there's no telling what the cause could be based on the symptoms alone. I have lots of neuropathy everywhere, and I'm gradually losing sensation in some areas; my joints make crunching noises like celery being twisted; the tendinitis flares up in my elbows and heels, which are the spots with frequent use; when I have a bad flare, I'll get this wobbly feeling like my head is made of gelatin; it's hard for me to warm up, and when I do the heat makes me feel a little ill. The worst symptom of all is a lack of energy, I have to move around like an old man, if I go quickly it makes me crash and the muscles in my feet and lower legs fill up with constant twitching.

The symptoms are all constant and get worse about quarterly. I don't take anti-inflammatories except for cannabinoids and supplements, which do help; no ibuprofen or acetaminophen, and steroids are a definite trigger for some floxies - I won't consider trying them.

This was in 2019. I had no choice but to walk away, I can no longer take any antibiotics without being floxed. When I noticed my health declining toward the end of the protocol, I let them know something was wrong, and the staff told me to continue on the maintenance meds. I did that for maybe two more months before the fatigue became too severe during the treatment week, so I discontinued. The last appointment I had with him he thought something was wrong metabolically, but he didn't connect it to Cipro.

Fluoroquinolone toxicity is a lot like Lyme in that some people get hit immediately, while others can go 6-12 months before they feel the effects. Unlike Lyme, there is no network of doctors for patients to go to, and it's not well understood. It's imperative that we identify who is at risk of this condition to prevent it, taking Cipro is a hell of a way to find out you shouldn't have when there is no recourse.

My body lost the ability to tolerate oxidative stress. I must be an extreme case because oxygen, which I tried during and after hyperbaric treatment, also causes flareups. Cancer and heart disease is the worst outcome of FQT, people die from it. I wouldn't trust any LLMD using Cipro after this experience, it's a dangerous med that can be worse than the diseases it treats.

dcd,

The clinic you went to - do they treat fluoroquinolone toxicity?

Rosi- I became allergic to Bactrim, had a painful peeling blister from Diflucan, and Flagyl began causing violent vomiting and weakness, which I think was a thiamine deficiency; then there was Cipro. After six months of IV and several more of orals, I still have treatment response from herbals to Lyme, Babesia, Bartonella, and likely mycoplasma. This is why I don't trust these aggressive protocols, it was the wrong approach for my case, and they had no means of determining that, at great risk to my health.

Dude- Thanks for those links, I hadn't heard of the FAAHA, I'll give them a shot if my current doctor is out of ideas during the next appointment.

bluelyme said...
bactrim did a number on me . mild sjs = major nerve damage . during the gulf war they didn't know if the syndrome was the mycoplasma or the prophylactic abx causing symptoms....genetic study prior to incident may have helped reveal sulfuration issues...hindsight is 20/20

. ...that's a tough 20/20 to look at and see it so clearly....I understand some cures are worse than the sickness, or something like that...anyhoo I've got foot neuropathy and shedding from poor circulation, psych. meds were a very bad idea, and I mean that in a serious, educated, cynical and very understanding and scientific way---it's hard to get that across when traditional psychiatry has gone haywire and blatantly corrupted... /end rant *sigh ..
being somewhat bedridden and got rhabdomyolisis from nervously pacing the hospital for an outrageously expensive and wish it could have been deemed less necessary than it turned out, I still have feeling and movement in my toes but they have been numb at the peripheries and pads of my feet, think it's "compartmentalisation" or something, maybe early diabetic sign or borreliosis-eating away again and I remember diabetes being a "side effect" of one of the heavier psych. meds they prescribed...sry to vent but I've had it with ER/psych. ward/hospitals....this disease is the worst, then you forget you have it, psych. ward docs won't give you a diagnosis unless you are covered head to toe in bullseye welts and a satchel full of live infected ticks lol but I digress..but what else causes that ungodly hopeless depression and all the weird tingling in my femur, feet soles and toes going numb at night..

Okay that's enough of my negativity for now (sry!) as this is sorta a "third space" https://en.wikipedia.org/wiki/third_place for me... so I have really been up and down, like almost seems like "mortally" depressed and then up to feeling sorta good now, I get these low spells where I forget to eat or take care of myself properly and everything's a chore...sure someone can relate. Anyway, acarined I hear you, this disease is miserable, made worse by the insult of "modern" medicine at times... (oof guess I wasn't done with the negativity lol) and bluelyme that mycoplasma fermentans is no joke, I've read alot back in the day about it. I think cholestyramine was in their (military grade) packs, I still have a ton of the stuff but it makes me beyond wobbly and affects my moods in a way that is disturbing to say the least.