Anyone quit disulfiram before reaching target dose?

Hey guys, just wondering if anyone quit disulfiram before getting to their target dose? I have been on disulfiram since last August. My doctor had me slowly ramp up but I can't even tolerate 187 mg without my skin going insane. I have developed horrible neck, chest and back acne since January.

I tried quiting disulfuram twice before for only one week periods. Each time my air hunger came raging back very quickly.

Everyone says that you feel crapy when stopping disulfiram for a few weeks. Im wondering if maybe my air hunger will disapate after a while. I have to quite because the skin issues are so incredibly bad.

Has anyone made progress from disulfiram even when they didn't reach their target dose?

Thanks blondie. I've never gone slowly off the drug. I think I'm at the point where I just want it to leave my body.

I really hope I get some improvements from putting my self through this for over 8 months.

my skin also worsened dramatically with acne like spots and papular rash when treating - i believe its an inflammatory sign - like a form of herxhiemer -

in fact skin lesions are known to worsen with antibiotic treatment in both syphilis and morgellons - so think its just a thing with treating spirochetes

i haven't fond anything that helps much - seems to just be a thing i need to get through

8 months of constant herxing sounds like a lot if you are not making improvements i would say something needs to be changed up especially if you cannot seem to get to target on disulfiram

perhaps worth discussing something babesia focussed - while trying to keep the spirochetes under control - if your main symptoms that return are babesia related

Morgellons is tricky - as its not fully understood

my own view is it is likely just a manifestation of lyme and maybe other infections like bartonella in susceptible individuals

some of my skin looks like Morgellons patients - no fibres though - but i do get little grains of hard material coming out of my pores - a number of people on the forum do also - often those with lyme and bartonella - i have lyme and bartonella -

i read some reports of ivermectin being helpful for some Morgellons people
and others where the symptoms clear up with typical lyme and bart antibiotics

Garzie, I too get the hard sandlike materials out of my pores sometime. However most of my skin stuff is nodular acne.

Rainy, are your skin issues related to disulfiram as well? If so, what dose were you on when you started noticing the skin stuff?

The various skin issues could be because you simply don’t detox well enough for any number of reasons - genetic, toxin overload, ongoing exposure to toxins. Treatment increases the toxin load both from killing pathogens and also your organs have to process and filter the drugs themselves.

My liver and kidneys look good on paper, but I don’t detox well at all and have always seemed more affected than others to various toxins, even in childhood. Not sure why. I do know that TUDCA has noticeably helped me, but I still have to avoid toxins as much as possible.

I think the biggest skin issues I had was during the months after starting Fluconazole and then Nystatin. I believe yeast and mold produce some potent toxins. I also believe some, like me, are overly sensitized to fungal toxins, so we may react more violently to influxes of fungal toxins, whether exposed externally in the environment or internally due to die off.

I just did a search on Disulfiram and Candida and found this. Apparently Disulfiram is anti-fungal. That may be a reason so many find the drug so difficult. Most with Lyme have yeast issues. https://pubmed.ncbi.nlm.nih.gov/33358402/. That said, I definitely don’t think that’s the only issue. Disulfiram is used for alcoholics, and they should definitely have yeast overgrowth. I am not aware of Disulfiram having horrible affects on alcoholics, though, unless they drink alcohol, so has to be more to it than that.

Sorry for rambling. Just thinking out loud here.

Post Edited (WalkingbyFaith) : 5/12/2022 7:04:19 AM (GMT-6)

WBF no problem with the rambling. I'm glad to hear people's hypothesis and thoughts on the subject. Thank you for your input.

Rainy, thank for the response. Im sorry you have skin issues as well. I hope you can get some relief soon.

I have stopped the disulfiram and will stay off of it for at least a month to see if my skin gets better. If my air hunger stays away I won't even need to try disulfiram again.

Thank you Gettan. So far I got a little air hunger back but it is way better than before I started disulfiram. The skin issues have yet to subside completely. It has been 3 weeks exactly so hopefully with more time I will get there. The skin seems to be getting better but it is a very slow process.

I have had treatments in the past that brought out skin issues. Whatever is being killed off is responsible for the purple scarring. My skin will take some time to recover from these weird scars.