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Exercise with Oxygen Therapy and Citrulline

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Lyme Disease
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Posted 5/27/2022 6:44 PM (GMT 0)
Has anybody looked into Exercise with Oxygen Therapy (EWOT) for Bartonella? I found this blog which is interesting. It makes a lot of claims. I'm not an expert in the biology of these illnesses. This blogger claims that Bart uses a chemical called HIF-1 to replicate in endothelial cells (I think). The blooger claims that EWOT eliminates the inflammatory process that allows Bart live and spread. Here's the link:

http://lymesolution.blogspot.com/2018/06/why-exercise-with-oxygen-therapy-ewot.html

It's an interesting breakdown, but I'm not sure if this has any validity or not. Has anyone looked into this?

Citrulline!

I just recently bought some of this. Apparently it has similair mechanisms to L-arginine meaning it increases nitric oxide and dilates the blood vessels. I don't see much written in stone about dosage. What sources I could find claim that people have been taking up to 6 grams in trails for different conditions. I tried 1.5 grams yesterday and I was feeling a bit lightheaded. I had already been flaring and am in the middle of the intense part of my treatment cycle. I can't say this was caused by the citrulline. Has anyone tried this? I'm curious about experiences or added knowledge.

Thanks!
Posted 5/28/2022 3:01 PM (GMT 0)
interesting ideas - and i seem to recall reading about HIF-1 and bartonella in a different context - but the article left me wondering if it was really an advert for their own oxygen system
Posted 5/28/2022 3:45 PM (GMT 0)
this paper seems to say that one of bartonella's surface proteins BadA is responsible for triggering the HIF-1 directly leading to angiogenesis - which may argue against hypoxia being the key driver and therefore may argue against Oxygen therapies from being super helpful

https://tinyurl.com/2nh9evbl
Posted 5/29/2022 5:53 PM (GMT 0)
Thanks for input Garzie. Yeah, you are probably right. I was a fitness junkie before all this crap happened. I probably have a subconscious bias for everything that proclaims exercise as a tool to get better. I know better. If you could out-exercise this illness I would have done that already. I have tried. Didn't work lol.
Posted 5/30/2022 10:31 AM (GMT 0)
i am with you on the bias towards exercise - i also used to do a lot of mountain biking, squash, hill walking, snowboarding, gym etc - i actually wonder if i had this infection for a long time and this lifestyle was keeping me well.

i do agree though that you cannot exercise your way out of it - especially anything aerobic really sets me back - i can walk 3-4 miles at a decent pace - but if i try to run for even 100yards i will be super fatigued the next day - its crazy how sensitive to that i am.

i do feel exercise is a useful as part of an overall treatment protocol / lifestyle though - i find i can do strength training type exercises - and tolerate these OK within reason - so am doing a 30mins workout with weights each 2nrd or 3rd day now ( had to work op to this gradually from doing 20 body weight only squats initially) and can feel it making me stronger over time and fatigue reducing
Posted 6/1/2022 4:25 AM (GMT 0)
This would be beneficial for almost any condition I would assume. Pumping oxygen rich blood deep within my tissues was a key factor in my recovery. I didn't exercise with oxygen, but I would love too. Looked into it actually, but too expensive for me. Citrulline is amazing. It's one of the myriad of ingredients in my pre-work out drink. I feel great with it.
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