Baggio-Yoshinari Syndrome Borrelia Study

It seems to me this Brazilian disease proves most of that ILADS has been trying to claim for years.

https://www.mdpi.com/2076-0817/11/8/889/htm

Hmmm having trouble getting the link to work, luddite that I am.The actual title of study is "The Current State of knowledge on Baggio-Yoshinari Syndrome, Brazillian Lyme-Like Disease: Chronological Presentation of Historical and Scientific Events Observed over the Last 30 Years."

It's long but extraordinary. The neuro elements alone are distressing but exciting and validating, at least as far as I can understand them.

There's a lot here that confirms what most of us had thought. This is Bbss, the causative agent of Lyme! And their patients test negative on the CDC's 2T. Brazil had to develop and embrace a different algorthym. The insights into morphology that they demonstrate in their patients is reaffirming and gratifying. The reference to tertiary phase reminiscent of syphilis speaks volumes. I can go on and on.

I'm sorry I cannot do the link.

Post Edited (duncan) : 8/30/2022 3:09:50 PM (GMT-7)

Girlie, you rock!

This thing is long. I had to read it in bits and pieces over a few days. But imo it's worth it.

The irony? Who'd the Brazilian team come to the US for advice? Steere. Yet they still generated these results.

The name thing disappoints, but they note it's Bbss that is the causative agent. Period.

Some snippets. Keep in mind this is Borrelia Burgdorferi sensu stricto:

"B. burgdorferi, the etiological agent of BYS, can remain dormant for long periods of time (cases # 2 and 6) and progress into the tertiary stage of the disease. This stage can be defined by a wide range of symptoms that develop after months or years after the initial Borrelia infection in a person who has not been treated with antibiotics. Diagnosis of late stage neuroborreliosis generally leads to little improvement even after antibiotic treatment since spirochetes may cause chronic structural derangements in the brain with irreversible damage to the central nervous system. Chronic encephalitis may be a consequence of infection caused by Borrelia burgdorferi; however, inflammation and injury in the brain may be a result of autoantibodies [77]."

and

"Based on clinical analysis and progression of hundreds of BYS patients, viewed for almost 30 years, we propose to demonstrate the disease expression and progression of this serious and complex syndrome.
Localized acute infection;
Early disseminated infection;
Latent infection;
Reactive disease expression resembling CFS/ME;
Reactive disease expression resembling autoimmune or allergic diseases;
Unclassified disease expression."

and

"In our opinion, these camouflaged Borrelia burgdorferi sensu stricto, exhibiting pleomorphic atypical morphologies, possibly appeared in our country as an adaptive process to survive the conditions of Brazil’s ecosystem. This smart adaptation by Borrelia to ticks and reservoirs present in the country explains why BYS patients express low immune response against the spirochetes and justifies many of the clinical symptoms observed in Brazil, such as the incidence of recurring episodes, frequent reactivations (autoimmunity and chronic fatigue symptoms) and the need for extended periods of antibiotic therapy."

Post Edited (duncan) : 8/30/2022 12:28:39 PM (GMT-7)

Garzie, they are talking Bbss. It's Lyme, or a close facsimle. Think Masters disease and what the CDC did with that. Read the study. Forget the abstract. While you read, remember they were counseled by Steere. I imagine I might be able to see his influence in certain aspects, for instance perhaps "Syndrome" in the name.
.
But if I'm ILADS, I'm ecstatic.

If I'm CDC/IDSA/NIH, I'm hoping this little name thingee helps hide these findings.

They clearly state this is Bbss.

They clearly state the CDC 2T won't pick it up (just like the 2T misses Bbss in many if not most US Lyme sufferers), but they nevertheless know it's Bbss, so they had to tweak the algorithm. Which is what we should be doing here.

They talk in detail about the weird morphology and suggest this may be something to do with the spirochete evolving to Brazilian environments - but the forms are almost exactly what ILADS researchers and clinicians have been claiming for decades.

They say theyve demonstrated the Bbss can not only be asymptomatic - for years - but in fact latent and leap back into active state at any time.

They say that neuroBbss if not caught in time will be almost impervious to treatment.

Bbss = the species responsible for Lyme in the US, at least. The spirochete might be a little different, but it's a little different in the US depending on strain/geography/vector. There are a lot of strains vs species, Not all strains generate disease or symptoms. But this strain in Brazil is from the same species as the one that causes Lyme in the US, and comes strikingly similar in terms of symptoms as promoted by ILADS.

A rose by any other name would still be a rose....

Read the entire study.

Post Edited (duncan) : 8/31/2022 7:04:25 AM (GMT-7)

ITs crazy because they admit they have no idea how it got to brazil, and yet here we are.

I mean this thing is in Brazil and yet doctors in the US will still tell you its not in this or that specific state, and yet somehow it travelled from Connecticut to Brazil but can't find its way to Georgia?

From what I can ascertain, the Brazilians used G39/40 antigens to help prepare diagnostics. They employed the 2T, which didn't always fail, just generally. Sound familiar? So they modified the protocol. Fairly pragmatic approach.

I hear you about strain differences. Strain differences can matter.

But here is my takeaway: These researchers examined a species of spirochetal disease that maintream US medicine claims cannot behave in certain fashions except in exceptional cases, and they demonstrated that specific species not only could act and manifest disease in those fashions, but in a substantial portion of the infected.

Will they call it Lyme? No. Does it look and behave, in large measure, like how ILADS clinicians and researchers purport Lyme to? It sure seems so to me. Is it derived from the same species that gives rise to Lyme? This paper indicates Yes.

This is so reminiscent of both STARI and B Miyamotoi. We are cutting taxodermy hairs. That does matter, of course, but not to the patients who sport nearly identical diseases.

Garzie, if you removed some of the disease labels used in this paper, and you showed it to me, I'd be hard-pressed to imagine this was not a paper generated by ILADS. What it says about morphology, about disease progression, about difficulties in patients generating strong enough immune response to satisfy the egregious 2T...

Who is to say what is Lyme? Is the pathogen a spirochete? From the same species that creates strains B31 and G39/40 and 297 etc?

Does the fact that this Brazilian disease employ other vectors preclude it from a given disease label - no, of course not, it just means we were wrong to speculate the vectors were limited to two or so tick species.

Do the patients' symptoms and spirochete behaviors mirror Lyme in the US and parts of Europe? There's the issue. I suspect ILADS would argue many do, while the CDC/IDSA/NIH - not so much.

Personally, for me it's a spirochete that creates a disease whose virulence broadly matches one promoted by ILADS and refuted and denied by IDSA/CDC/NIH, and in fact, it's a specific species of spirochete that that same bifurcated, polarized debate has swirled around for 25 years. Labels notwithstanding, it's fairly clear how this study characterizes the behavior of this pathogen.

Post Edited (duncan) : 8/31/2022 6:49:38 AM (GMT-7)

Agreed.