yep there are lots of theories - but very little evidence, if any( that i know of) that pulsing is more effective than a continuous dose for ceftriaxone
most of the trials that are published for Ceftriaxone are continuously dosed
if you have any - please do post it up
BTW - most LLMD's that use pulse approaches ( Dr J, Dr SM etc ) tend to use much longer pulse durations for lyme - eg 3 weeks on 1 week off - 2 weeks on 2 weeks off - - and these are usually combination abx protocols with 2 or more abx from different families involved. so i am not sure of the basis for the 4 day on 3 days off approach
maybe there is a trial that i dont know of - or maybe its just one LLMD's personal preference - or maybe he is concerned about
ABX side effects or some other reason.
Post Edited (Garzie) : 11/10/2022 2:06:00 PM (GMT-8)