Is it Odd to Have Low White and Red Blood Count at Same Time?

Can Lyme or co-infections cause low red (3.55) and white blood cells (2.6) at once? Also low hematocrit (11.9) and hemoglobin (34.5).

Everything comes up as aplastic anemia.

Thank you for response, Garzie. Blood test results set me off when they aren’t good, and the reds and whites have been low or low normal for a number of years. Rarely are they both at same time. Same with hematocrit and hemoglobin.

With Sjogrens in play, I don’t know what is what. Trying to treat it all but then the frickin kidneys. Thanks for your taking the time to look.

MCV -97 (high end of normal)
MCH - 33.5 (barely high)
MCHC - 34.5
RDW - 12.1
Platelets - 178
Neutrophils-50
Lymphs - 32
Monocytes - 13
EOS - 3
BASOS - 2
Neutrophils Absolute) - 1.3
Lymphs (Absolute) - 0.8
Monocytes (Absolute) - 0.3
EOS - (Absolute) -0.1
BASO (Absolute) 0.1
No immature granulocytes

as you say RW - its not unusual for you to have low counts of either - and then its just a matter of chance whether you will get low on both once in a while - so i don't think there is any need to read any more into it than that

if you only look for the negative side of any test - you will always find things to freak you out - but i don't think there is any real new news here.

these illnesses cause suppressed counts for lots of people here - differing degrees for different people but the trend is clear

The normal platelet count is between 150 and 400 x 109/L - so again - just low normal - which fits well with the other results - of just general low production of all cell types

MCV on the high side tends to indicate a higher proportion of younger red blood cells vs older - they gradually shrink a little with age - which is consistent with red cells being consumed early
bart will do that - but i have had high normal readings for this one for years - and it doesnt represent anything new to worry about

MCH is as you say only fractionally over the upper limit - most clinicians would take no notice over such a small elevation - and again i have had many similar readings so i don't think its any cause for concern. High MCH value can be caused by anaemia due to a deficiency of B vitamins, particularly B-12 and folate. yours is not really in a danger area type range but for peace of mind you might want to test your B12 and folate levels but that's about it.

i guess what i am trying to say is there is nothing i see here to indicate a new problem of something to worry about - more that these are just expected downstream effects of infection and or auto-immunity - which you know about already - and i dont see any new health consequences or actions needed as a result - except maybe checking your B vits - as its worth keeping those in the normal range with anything to do with neuropathy .

in fact if this test lead you to find hat either folate or B12 was low - that would actually be a good outcome from the CBC results - as its something that may well help you

Post Edited (Garzie) : 1/24/2023 8:37:32 AM (GMT-8)

running wild said...
I thought if you when I saw the results., dcd. Instead of the body helping, it does the opposite. What’s your next thought on possible help?

You can take as much b-12 as you want, its not toxic in large doses

I actually started taking hydroxycobalamin IM shots 2 weeks ago. My b12 is always low. while it doesnt stop the autoimmune attack, i have noticed that my allodynia/nerve damage feels better for a few days after the shot, and i dont think its placebo since i wasnt expecting that. There's evidence it helps w/ regeneration.

Right now I'm planning on asking my neuro to move IVIG to once every 2 weeks. I'm much better than I was this summer w/ my immune system, where I was flaring non-stop uncontrollably every day, but i still have some flares now. Some evidence a larger dose once every 2 weeks is more powerful.

The issue seems to be right now that even when i'm not flaring, i'm in pain in my hands and feet from nerve damage. I've come to estimate that 60% of my pain now is from nerve damage, and not active inflammation. 3y ago that number was more like 10%. And hwat happens is even a miniature flare for a day, and everything is raw again because the nerves are already damaged, and I'm starting back from 0 having undone any healing that might have occured.

So healing nerve damage is also a priority for me now. I'm going to get a prescription for Clemastine Fumarate for that.

There are several studies and a couple on going ones showing that Clemastine remyelinates nerves in MS. Winsantor who is still tryign to get funding for their phase 3 trial for Pirenzepine has proven that pirenzepine regrows nerves.

Both Clemastine and Pirenzepine have action on the M1 receptor, and inhibiting it seems to induce nerve growth through a mechanism which has been dubbed "cholinergic restraint"

This video is pretty cool
https://www.youtube.com/watch?v=t6p5e2tcr9q

Shows the actual myelin rings growing using a electron microscope
https://ibb.co/tbdc7bk

Of all the 100s of drugs this researcher tested for nerve regeneration, every single one that was effective was an M1 antagonist, with Clemastine being the strongest
https://ibb.co/s2dpgxm

I'm also part of a group which is synthesizing a selective HDAC6 inhibitor through some connections at a lab. There's evidence that HDAC6 inhibitors can regrow nerves in pretty poweful fashion by literally rebuilding the tubulin to the dead nerve and refeeding it. One of the companies working on an HDAC6 was able to show near full restoration of nerve function.

Obviously neither of these cures my disease and rights my immune system, but I'm trying to reverse some of the extensive damage to lower my pain, and with reduced flares from the IVIG i should be in business.

All in all better than i was a few months ago tho, i think. The HBOT really did help calm the arthritis a bit, knock on wood, and the ivig has calmed the daily nerve flares. If i just didnt have this extensive f'ing nerve damage may i could have a few pain free days

Post Edited (dcd2103) : 1/24/2023 10:45:22 AM (GMT-8)

Dcd - You have tried so many things to find relief. And there have been times you have felt somewhat better.

The IVIG seems to have really made a difference, so hoping the Clemstine Fumarate keeps adding to that.

Garzie- Awesome to see you continue to make progress and you are in best place in years. Improvement breeds hope.

My guess is I’m low in folate. I do supplement some with B vitamins, with main being 12.

Dcd - You have tried so many things to find relief. And there have been times you have felt somewhat better.

The IVIG seems to have really made a difference, so hoping the Clemstine Fumarate keeps adding to that.

Garzie- Awesome to see you continue to make progress and you are in best place in years. Improvement breeds hope.

My guess is I’m low in folate. I do supplement some with B vitamins, with main being 12.

Hey running wild, I'm not sure I think they were for Lyme as it was on a Lyme forum.
I found 3 of the reviews again:

Somebody said...
6 months ago. Still being flared from them.

I got fetal stem cells, in Ukraine, and wow. Never again. DO NOT DO IT. IT IS DANGEROUS. It is a total gamble and if it doesn't work out you will be sorry.

Are you sure people recovered from the stem cell flares?? I am feeling almost suicidal that I've ruined my life forever.

I got a crazy anti inflammatory effect from them which felt amazing BUT also started flaring at the same time. Over time, the anti inflamm effects are fading but the flare continues, and each month it's like they stirr up different symptoms.

What they made worse: hair loss, periods stopped for a few months, flu like feeling, energy envelope (get exhausted after talking now even), acid reflux, neuropathy so much more worse, random aches and pains, insomnia WAY worse, totally reversed circadian rhythm, protein in urine I could go on and on.

DO NOT DO IT consider yourself warned. I don't care about recovery anymore. I want to go back to the pre stem cell me.

And:

Somebody said...
Just wanted to write this to spread awareness. I’ve had Lyme since 2019. Did antibiotics for a year, got better, got on herbals and symptoms started coming back in March. My friend told me stem cell in Mexico with doctor calzada cured her, so I went. I’ve been desperate for 3 years to get my life back. I trusted the process completely. The clinic was beautiful and they used ozone therapy for 4 days, stem cell injection shots for localized places of your choice, and then IV stem cell your last day.

My main symptom was trigeminal neuralgia, which affects the nerves on your face, so I got stem cell shots in my face. BAD move. I came home from Mexico and trusted the Herxing process. After about a month and a half, I realized it was a full blown flare, not herxing. I had severe MS symptoms, seizures, and not might have to get my gallbladder removed. My face looks completely different because the shots moved the infection into my eyes, teeth and nose. It’s been absolutely ****** brutal.

Again, I’m just writing this so people know we are all different, and what might work for one person might not work for another. I’d do anything to have my old symptoms back.

Good luck 🤍

And:

Somebody said...
I got stem cells in July. Most of the symptoms are in my face. It’s been ***** BRUTAL. All of my neuro issues were gone after initially treating for a year with a doctor. Got stems- not my most has collapsed, jaw shifted and have to get braces, MS symptoms when I came home that gave thanks fully gone away. I’ve been too afraid to get back on antibiotics again. Been doing natural stuff but it isn’t touching it. May go to lymestop. Stem cells are a ***** death sentence.