Treating for gut pathogens helping fat malabsorption (and insomnia)

Update on my mysterious digestive problems that started in June 2023, and it seems like my insomnia might be a related symptom of that.

After obvious evidence of fatty stools for almost 2 years, without me explaining the details, lol, the digestive doctors only found one thing which was low pancreatic enzymes. They only tested for one of the H pyloris also, Which was negative. It kind of seemed like it might’ve been some sort of a bile duct blockage, problem, but digestive doctors don’t really test or do anything for that.

Adding supplemental enzymes and ox bile seem to help, but not really that much. I was also eating a low carb diet, which has a little more meat in it than a normal diet, and this made things even more difficult.

After running out of ideas,I recently decided to use some of my old supplements from when I had digestive candida many times in the past, which I developed antibodies in blood tests several times before.

I call those “hot” herbs, and even though the now brand and other brands are aimed towards Candida, they can kill off other digestive overgrowth as well.

In the past when I had Candida, it was more upper digestive stomach, and higher. But I also had itching all over my body. What I had going on this time seems to be more intestinal , which I’ve been reading about it is also possible and I also had more general overall body itching.

I did not retest antibodies this time, Just started taking Anti-candida supplements. Then all of a sudden what I’m leaving in the toilet starts to look more “normal”. And although not April fresh, It certainly didn’t smell like a skunk just wandered through my bathroom (Like before).

What I am wondering is, if someone can have a more localized pathogen infection in one of the bile ducts Creating temporary blockage. It’s almost like Killing off digestive pathogens improved my natural bile duct flow.

(I did a gallbladder flush, which took around three days from start to finish one weekend last January which really did nothing for bile flow or make any change to what I’m flushing down the toilet)

And Oddly enough that my gut seems to be working more normal, I seem to be sleeping better.

My gut has improved more than my sleep has,…so I don’t want to totally jinx myself, but they Certainly seem related to each other.

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Just one of many sites about gut health and insomnia (this one is just a health coach), There are better websites, this is just an example of what Ive talked about in this post for those who might be new to this:

https://thesleepdetective.com/post/what-s-living-in-your-gut-can-cause-insomnia-h-pylori-candida-and-parasites

Post Edited (astroman) : 4/6/2024 2:06:58 PM (GMT-8)

It’s possible just to have a clogged bile duct no? Ultrasound could be helpful there or some sorts study where they inject dye (although I try not to do the radioactive one at all unless the benifit>risk).

I know RBC infections can make home in liver cells. I was also treated with biltricide which is great for liver flukes (not sure if I ever had those or not).

Something I’ve been looking at lately for myself is TMG (to better methylate homocysteine). This was coming off of my genetics report. I have a histamine gene mutation that causes an increase in homocysteine. This was confirmed before testing as I can’t tolerate NAC at high doses I just feel bad, at low doses I get itchier.

Interestingly my upper right quadrant pain has improved a bit since I’ve added TMG with breakfast (although it returns into the evening with digestion of my last meal). I’m reading it also helps with fat digestion. So now I’m wondering what % of this discomfort was more from digestion vs a more “danger” style inflammation/toxicity. Planning to add an evening dose soon to see if this backs my theory.

I also find a digestive enzyme helpful. Which is bile but also some other jazz.

astroman said...
Loski01-

My functional doctor ordered a homocystine test. I have not done it yet.

Do you know offhand what gene that’s related to? If so, I will look it up on my gene test results.

My report looks at HRH1, HRH4, DAO, HNMT, NAT2, MAOA, MAOB, ALDH1B1 and ALDH2 for histamine. SAM is relevant here too which was the one that recommended TMG for me + with a story I put together from my histamine profile (which isn't terrible but more mixed - SAM was more the idea ). "Notable variation:
SNP: BHMT 716G>A rs3733890 (-/-, GG) 
This GG wild type has a higher Km value and lower substrate affinity than the variant which means it may work more slowly. This means that there is potentially lower capacity to recycle homocysteine via the "short route" in the liver compared to variant forms."

I'm still sifting through all this data and learning the ins/outs.
My other big discovery so far was my MTHFR is mutated reducing b2 binding ability, slowing MTHFR by 50-75%. So I've upped my b2 significantly, and added another 500mcg of folate in AM.