Low ch50

from what i have read it can be difficult to interpret as a standalone test

it can be low in some auto-immune diseases - as more of the complement is getting used up by those reactions - but it can also be low due to the liver simply not making enough - for any number of reasons

i think for this reason it is usually used in conjunction with a bunch of other tests to help figure out what might be going on

or may be used as a first round screening test when something else is suspected

overall - many / most people with chronic lyme have some kind of auto-immunity going on - so i would not read to much into the CH50 result on its own

Hey Bailey, it says that malnutrition can cause low ch50 at this link below.
I know that you have trouble tolerating many foods.

"Decreased complement activity may be seen in:
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Cirrhosis
Glomerulonephritis
Hereditary angioedema
Hepatitis
Kidney transplant rejection
Lupus nephritis
Malnutrition
Systemic lupus erythematosus
Rare inherited complement deficiencies"

Maybe it could also be something less specific like just fighting the infections:

"The proteins work with your immune system and play a role to protect the body from infections, and to remove dead cells and foreign material."

Both quotes from here: https://www.mountsinai.org/health-library/tests/complement

Interesting, I’ve never heard of CH 50.

As you also mentioned C4a, mine was super high at 50,000!

After antibiotics it dropped down to 1400 ,which is normal. Ive had it checked several times after. Last time was pre-covid, Prob should test again.

One igg class is high, but within the range? (Not above range?).