Does herbs treat intacellular lyme and co-infections?

I had been on antibiotics for lymr disease and co-infections for 1 year. Out of all the most effective antibiotic was azitromicyn. I only took it for 21 days, but it has done miracle for me. Never in 8 years i didn't feel so much muscle strength even ifbi trained every day. I haf big muscle weakness before.
Now after i stop tooking it every day it goes worse for a little bit and it will return to the same level as before(my symptoms). Been taking herbs recently for lyme and bartonelly as well as mycoplasma and i am interested if they can treat lyme in cells (intracellular lyme disease)

Are you asking if herbs are able to treat intracellular borrelia as well as an antibiotic like azithromycin does? An easier question to answer might be if you are asking about babesia and bartonella being treated to kill them as they try to protect themselves by being intracellular in red blood cells?

The studies I'm aware of show the effect of plants and essential oils on biofilm, cyst and planktonic forms of borrelia. Eva Sapi of the University of New Haven studied Samento and Banderol for their in vitro activity against cyst forms, planktonic forms and biofilm forms of borrelia.

A Johns Hopkins research team has done a series of studies of antibiotics, essential oils and plants for in vitro activity against borrelia, babesia and bartonella. Johns Hopkins found Cryptolepis, Cat's Claw, Japanese knotweed, Black walnut and Chinese Skullcap all had significant in vitro activity against cyst, planktonic and biofilm forms of borrelia.

I haven't gotten deep into the weeds of the papers that Johns Hopkins put out regarding their babesia and bartonella studies. I don't know if they were using infected red blood cells. This is a readable web page that will sum up the research. Or you could search for the original papers if you want more details. When I want to find them, I search for "Johns Hopkins babesia plants" and so on.

https://www.lymedisease.org/herbs-against-lyme-bart-babesia/

I'm not aware of infected cell lines being developed to study intracellular borrelia. I do know that both Eva Sapi's research team and the Johns Hopkins research team are planning to do animal studies next. Eva Sapi is trying to develop a zebrafish model of Lyme. Johns Hopkins will be using mice, I think.

in many cases we do not have teh in depth studies to show the exact mechanism of herbs or their components on bacteria or other microorganism

the main reason being because there is little money to be made from such research - naturally occurring herbs cannot be patented - only synthetic chemicals or processes -
whereas a drug can be patented and can therefore return a profit that will pay for such research on the properties of drugs

that said we can infer some general rules that likely apply
fat soluble chemicals like carvacrol from oregano are very likely able to penetrate the phophpholipid membranes of many cells and once inside are very likely to be active for intracellular organisms that are sensitive to it

other compounds that are oil soluble or just small molecules that pass across membranes well are likely to be active intracellularly also

however i would just caution that although it is indeed important to target intracellular organism
they are not the only form that causes persistent illness
persister cells are another very important form to tackle
and biofilms are another
all 3 of these mechanisms allow persistence of infection during treatment and relapse after treatment
so all treatment plans for chronic infections should target all three

many drugs and antimicrobials target more than one of these mechanisms and not all actions of all such compounds are well understood
so it may be easy to assume its a single action that was critical to the outcome - when in fact its usually the combination that has the impact

overall - i am all for using herbs - i use them myself extensively
but i would also just state that logically - once in the chronic stage this is often an extremely difficult disease to beat -
finding a treatment that works for you is like finding a pot of gold - so i would say - if antibiotics worked well for you - unless there is a serious known medical risk involved you continuing to take them - they are probably the most likely thing to get you to remission.

i hope its of some help