Less commonly used Babesia herbs

Hello,

Hope you are all doing well!

I compiled a list of herbs and/or herbal compounds that could in theory, potentially be used to treat Babesia. It took me a while to find these and put them together and feel like it's worth sharing.

Keep in mind that these are often just 1 or 2 studies and haven't been tried in humans. So there is absolutely no guarantee that they will work. They might,... but they also might not. I'm just posting these here so people can look into them, but I'm not saying anything on whether you should try them or not. That's up to you.

I should also say that it's important to check for side effects before starting a herbal treatment. And finally, some of these have only been tested on different strains of Babesia, for example some of the studies looked into strains that are usually only found in animals.

The ones I personally found the most interesting were Moringa leaves, Sumac and a different type of Artemesia from what we usually use.

With all of that said, here is what I found:

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Moringa oleifera Leaves

Evaluation of the Inhibitory Effect of Moringa oleifera Leaves Methanolic Extract against In Vitro Growth of Several Babesia Species and Theileria equi and the In Vivo Growth of Babesia microti.

https://pubmed.ncbi.nlm.nih.gov/37941580/

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Berberis vulgaris/Berberine

Antibabesial activity of protoberberine alkaloids and 20-hydroxyecdysone from Arcangelisia flava against Babesia gibsoni in culture

https://pubmed.ncbi.nlm.nih.gov/15750325/

Phytochemical Screening and Antiprotozoal Effects of the Methanolic Berberis Vulgaris and Acetonic Rhus Coriaria Extracts

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7037273/

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Black Seed Oil/Thymoquinone

Evaluation of the in vitro and in vivo inhibitory effect of thymoquinone on piroplasm parasites

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc6335684/

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Garlic and Black Pepper Oil

Identification of Essential Oils Including Garlic Oil and Black Pepper Oil with High Activity against Babesia duncani

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7350376/

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Sumac/Rhus Coriaria

Phytochemical Screening and Antiprotozoal Effects of the Methanolic Berberis Vulgaris and Acetonic Rhus Coriaria Extracts

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7037273/

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Artemisia herba-alba (different type of Artemisia)

Evaluation of the in vitro and in vivo inhibitory effects of Artemisia herba-alba against the growth of piroplasm parasites

https://pubmed.ncbi.nlm.nih.gov/35891656/

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Capsicum annuum

Effect of methanolic extract from Capsicum annuum against the multiplication of several Babesia species and Theileria equi on in vitro cultures, and Babesia microti in mice

https://pubmed.ncbi.nlm.nih.gov/35369597/

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Rottlerin, Narasin and Lasalocid acid

Discovering the Potent Inhibitors Against Babesia bovis in vitro and Babesia microti in vivo by Repurposing the Natural Product Compounds

https://pubmed.ncbi.nlm.nih.gov/34912876/

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Ginger

Evaluation of the inhibitory effect of Zingiber officinale rhizome on Babesia and Theileria parasites

https://pubmed.ncbi.nlm.nih.gov/34352378/

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Achillea millefolium essential oil

Anti-babesial potential and chemical composition of essential oil from yarrow Achillea millefolium

https://pubmed.ncbi.nlm.nih.gov/33847097/

In vitro antioxidant and antibabesial activities of the extracts of Achillea millefolium

https://pubmed.ncbi.nlm.nih.gov/31269341/

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Xanthohumol and Gossypol

Xanthohumol and Gossypol Are Promising Inhibitors against Babesia microti by In Vitro Culture via High-Throughput Screening of 133 Natural Products

https://www.ncbi.nlm.nih.gov/pmc/articles/pmc7711813/

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Viola tricolor and Laurus nobilis extracts

Gas chromatography-mass spectrometry analysis, phytochemical screening and antiprotozoal effects of the methanolic Viola tricolor and acetonic Laurus nobilis extracts

https://pubmed.ncbi.nlm.nih.gov/32183812/

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Syzygium aromaticum and Camellia sinensis

Inhibitory effects of Syzygium aromaticum and Camellia sinensis methanolic extracts on the growth of Babesia and Theileria parasites.

https://pubmed.ncbi.nlm.nih.gov/31101552/

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Pulsatilla

Flavonoids isolated from the flowers of Pulsatilla flavescens and their anti-piroplasm activity

https://pubmed.ncbi.nlm.nih.gov/30847754/

That's it for now, take care!

Buhner recommends these in his books and they've proved successful for people in the facebook groups. They're noted in an offhand way as he hadn't had first hand experience with them. I think that his partner Julie McIntyre has used it too.

Brucea Javanica:

Evaluation of efficacy of bruceine A, a natural quassinoid compound extracted from a medicinal plant, Brucea javanica, for canine babesiosis
https://pubmed.ncbi.nlm.nih.gov/19194074/

Screening of Indonesian Medicinal Plant Extracts for Antibabesial Activity and Isolation of New Quassinoids from Brucea javanica
https://pubs.acs.org/doi/10.1021/np070236h

Buhner recommends this one in his book along with this one:

Nauclea Latifolia

Betulinic and ursolic acids from Nauclea latifolia roots mediate their antimalarial activities through docking with PfEMP-1 and PfPKG proteins
https://funaab.edu.ng/effects-of-trypanosoma-brucei-and-babesia-microti-infections-on-the-primary-granulomatous-reactions-to-schistosoma-eggs-laboratory-animals/

In vitro Antiplasmodial activity and Cytotoxicity of some Medicinal Plants indigenously used in Nigeria against Malaria.
https://www.researchgate.net/publication/281409505_in_vitro_antiplasmodial_activity_and_cytotoxicity_of_some_medicinal_plants_indigenously_used_in_nigeria_against_malaria

You're welcome

I think I may have seen Nauclea mentioned once or twice before.

Brucea smells like chocolate - which is really nice but oh my word it's one of the most bitter herbs I've ever tasted.

Also it's a bit like that other herb, used for bartonella - it smells like rotten cabbage and you need to boil it and tincture it. Anyway it's necessary to take breaks for the kidneys.

I just remembered it, it's called Isatis! It's supposed to be a super potent antimicrobial - but not for babesia.

Interestingly, several of those herbs also lower histamine/inflamation. Moringa, ginger, black seed. I take all 3 of them. Maybe there’s a causation link? Like babesia raises histamine or causes mcas issues, therefore using those herbs reduces histamine/mcas symptoms?

thank you so much! i just added berberrys to my protocoll, and now i understnad why i am so tired, it hits the babesia!
has anyone some expiernce with Nauclea Latifolia ? It should work a bit like crypto...

yeah thanks fergleman, i am in the babesia buddy group already, its a cute group

The end of the second day of trying yarrow is here, I took 150 mg today.
I had brainfog today, not sure if it was related. Will go to 400 mg tomorrow and find out.