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Please help me understand my Igenex results!!!!

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Posted 12/31/2013 8:08 PM (GMT 0)
IGENEX IGG
CDC NEGATIVE

18KKDA -
23-25 -
28 -
30 +
31-34-
39 IND
41 ++
45 KDA -
58 ++
66 -
83-93 -

IGENEX IGM POSITIVE
CDC POSITIVE
18 +
23-25 +
28 -
30 +
31 +
34 IND
39 +
41 +
45 -
58 -
66 -
83-93-
COULD SOMEONE PLEASE EXPLAIN WHAT THE POSITIVES MEAN AND THE DIFFERENCE BETWEEN IGG AND IGM?
Posted 12/31/2013 8:53 PM (GMT 0)
Hi Tracy,
IgM are the antibodies that are produced within the first 4 - 6 weeks of the infection, and can spike during the course of the infection.

IgG are antibodies that are produced later - usually indicating a chronic infection.

You are showing a reaction to several bands that are specific to Lyme disease in your IgM and you IgG results. This means that you have this bacteria in your body - otherwise there would be nothing for your body to respond to. I'll go over the bands that showed a response, and the ones that are specific to Lyme that you reacted to.

IND = indeterminate, meaning that something reacted, but it wasn't strong enough to bring it to a full positive result.

In the IgG results (indicating a later response):

Band 30 isn't specific to Lyme and can cross react with other things.

Band 39 is specific to Lyme however, and indicates BmpA - Bacterial membrane protein "A"

Band 41 - often shows up, as it is the "tail" of the bacteria - but there are several other bacteria that have this same "tail" so it's not specific to Lyme.

Band 58 - this band has not been positively identified as of yet.
----------------------------------------------------------------------------------
IgM responses:
Band 18 - this is also indicating the "tail" of the bacteria and can cross react with other bacteria of this type (spirochete).

Bands 23 - 25 - this indicates Osp C - Outer surface protein "C" and band 25 is specific to Lyme.

Band 30 - as above in IgG - not specific to Lyme

Band 31 - OspA - Outer surface protein "A" - specific to Lyme disease

Band 34 - OspB - Outer surface protein "B" - specific to Lyme. Even though you only got an IND on this, it's still counted as a positive.

Band 39 - BmpA - same as in the IgG response - specific to Lyme.

Band 41 - again, this is indicating the tail of a spirochete bacteria - not specific to Lyme.

I hope that has answered your questions! Congratulations on your positive test result!! I hope that you get the treatment that you need.
Posted 12/31/2013 9:12 PM (GMT 0)
Thank you Traveller!!!
is this a strong positive for lyme disease then? because it is cdc positive does that mean that main stream doctors will agree that I do have lyme disease?
Posted 12/31/2013 9:14 PM (GMT 0)
Also 83-93 says IND I accidentally left that out on the IGM result. What does that mean?
Posted 12/31/2013 9:36 PM (GMT 0)
Bands 83 & 93 are also specific to Lyme disease. This strengthens your CDC positive result.

Unfortunately, many docs will still not acknowledge even a CDC positive test result. We even have had a member here go to a "supposed" LLMD with a CDC positive WB and was told that it's all just due to her anxiety, so do be careful to not believe the lies and find a good LLMD or Holistic doc to seek treatment from.

Even if main stream docs will acknowledge a CDC positive WB, it doesn't mean that they understand the condition well enough to effectively treat it, and if there are complications (like most of us have) they will truly be lost and you will loose some of your healing while they try to figure out what happened.
Posted 12/31/2013 10:04 PM (GMT 0)
Thank you Traveller. How long were you in treatment for and what route did you go? Do you have a post with your symptoms and treatments?
Posted 12/31/2013 11:11 PM (GMT 0)
LOL! No, I don't have a post with my symptoms and my treatments, but I am going to be creating one very soon, as I've had a lot of requests lately!

At first I went the abx route, but that ended with me being much worse off that when I started, so I went with Holistic treatments. The only one that would take me on was a wonderful Practitioner of Traditional Chinese Medicine, Acupuncture and Western Herbalism. She stuck with me during the 2 1/2 years of treatment that I needed, which was an amazingly fast time for my healing. All other docs estimated I would be in treatment for 10 or more years. smhair But I was more than willing as long as I could feel better!
Posted 1/1/2014 3:11 AM (GMT 0)
Can I ask how you were diagnosed?
Posted 1/1/2014 5:04 PM (GMT 0)
I was diagnosed clinically - by symptoms. My Western Blot at the time of my diagnosis only had a positive for Band 41 - like many here. It wasn't until I had a full 12 months of very strong (even by our standards) doses of Minocycline that I tested CDC positive for Lyme and RMSF.

Which is how I know that even a fully CDC positive on the Western Blot won't get most main stream doctors to do a darned thing!! The ones that were nice about it would tell me; "The doctor doesn't want to take on such a complicated case at this time. I'm sorry." and that was it! I was sent on my way ....to die for all they cared, and it almost happened as my adrenals were on a bad downward trend.

According to the symptoms I suffered with, I was infected when I was 7 yrs old with RMSF, Bart by the age of 8 and Lyme arthritis (late stage symptom) at the age of 9. I lived with on again, off again debilitating symptoms through out my life. I was finally diagnosed at the age of 44 by a LLMD that has since passed away - Dr. Edwin Masters - with all the tick-borne infections and several viral infections.

As for my symptoms, have you seen our symptom lists in the "New to Lyme?" thread? In the Master symptom list for Lyme disease, I had all but the worst of the heart symptoms, and the male only symptoms - in other words all but a few. I had all the other symptoms of the other infections as well - except for rashes. Most of my rashes were more nondescript other than occasional Bart rashes.
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